Evidence map›Paper›PMID 31669973›Full record

ArticleRedox biology2020

Metformin protects against PM

Junling Gao, Juntao Yuan, Qiao'e Wang, Tong Lei, Xiyue Shen, Bingqing Cui, Fang Zhang, Wenjun Ding, Zhongbing Lu

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Acute Lung Injury and the NLRP3 Inflammasome.Journal of inflammation research · 2024
    Review
  10. Influence of Metformin Discontinuation on Readmission Rate in Patients With Acute Heart Failure.Journal of community hospital internal medicine perspectives · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Metformin alleviates chronic obstructive pulmonary disease and cigarette smoke extract-induced glucocorticoid resistance by activating the nuclear factor E2-related factor 2/heme oxygenase-1 signaling pathway.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Junling GaoCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Juntao YuanCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Qiao'e WangKey Laboratory of Cosmetic, China National Light Industry, Beijing Technology and Business University, Beijing, 100048, China.
Tong LeiCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Xiyue ShenCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Bingqing CuiCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Fang ZhangCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Wenjun DingCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: dingwj@ucas.ac.cn.
Zhongbing LuCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: luzhongbing@ucas.ac.cn.
University of Chinese Academy of Sciences · CNBeijing Technology and Business University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fine particulate matter (PM

Indexed as

AMP-Activated Protein KinasesAnimalsBiomarkersBiopsyCell LineDisease Models, AnimalDisease SusceptibilityEchocardiographyFibrosisHeart DiseasesHumansLung InjuryMaleMetforminMiceMice, KnockoutAMP-Activated Protein KinasesBiomarkersMetforminParticulate MatterPrkaa2 protein, mouseProtective AgentsAMPKα2Cardiac dysfunctionLung injuryMetforminPM(2.5)

Identifiers

PMID31669973
PMCPMC6838896
OpenAlexW2981148010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.