ArticleDrug and alcohol dependence2019
Increased neural activity in the right dorsolateral prefrontal cortex during a risky decision-making task is associated with cocaine use in methadone-maintained patients.
Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Adaptations of the balloon analog risk task for neuroimaging settings: a systematic review.Frontiers in neuroscience · 2023Pooled it
- Neuroimaging in Addiction: Principles of Functional Near-infrared Spectroscopy and Its Emerging Role in De-addiction: A Narrative Review.Annals of neurosciences · 2026Review
- Applications of Functional Near-Infrared Spectroscopy (fNIRS) in Monitoring Treatment Response in Psychiatry: A Scoping Review.Journal of clinical medicine · 2025Review
- Multiomic Network Analysis Identifies Dysregulated Neurobiological Pathways in Opioid Addiction.Biological psychiatry · 2025Article
- Recommendations for Diagnosing and Quantifying treatment outcomes in clinical trials of compulsive sexual behavior disorder.Addictive behaviors reports · 2025Review
- Review of cocaine-induced brain vascular and cellular function changes measuredNeurophotonics · 2025Review
- Friend or foe: classifying collaborative interactions using fNIRS.Frontiers in neuroergonomics · 2023Article
- Prefrontal fNIRS-based clinical data analysis of brain functions in individuals abusing different types of drugs.Journal of biomedical semantics · 2021Article
- Neural correlates of cognitive control in women with a history of sexual violence suggest altered prefrontal cortical activity during cognitive processing.Women's health (London, England)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMethadone maintenance is an effective treatment for opioid use disorder (OUD), yet many methadone-maintained patients (MMPs) struggle with cocaine use during OUD recovery. The current study aimed to identify whether prefrontal cortex (PFC) activity during a risky decision-making task was associated with cocaine use during a 90-day follow-up in MMPs.
methodsMMPs (N = 28) attended a single neuroimaging session wherein PFC activity was measured using functional near-infrared spectroscopy (fNIRS) during the Balloon Analogue Risk Task (BART). Trait impulsivity was assessed via the Barratt Impulsiveness Scale version 11 (BIS-11). Following the neuroimaging session, MMPs were tracked via electronic health records for 90 days to determine treatment outcomes including cocaine use verified by urine drug screens.
resultsDuring the BART, MMPs who used cocaine displayed increased neural activity in the right PFC during active decision-making (F
conclusionsThe fNIRS device is portable, relatively easy to use, and potentially feasible for use in methadone outpatient programs to assess propensity for negative treatment outcomes such as continued cocaine use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.