Evidence map›Paper›PMID 31669409›Full record

ArticleNeuroImage2020

Using a multimodal near-infrared spectroscopy and MRI to quantify gray matter metabolic rate for oxygen: A hypothermia validation study.

Mada Hashem, Qiong Zhang, Ying Wu, Thomas W Johnson, Jeff F Dunn

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. 1H-NMR-based metabolomics reveals that prior exercise modulates metabolic changes in the cerebral cortex and hippocampus in sleep-deprived mice.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  2. Article
  3. Review
  4. Quantitative Optical Imaging of Oxygen in Brain Vasculature.The journal of physical chemistry. B · 2024
    Review
  5. Article
  6. The relationship between cytochrome c oxidase, CBF and CMROJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mada HashemBiomedical Engineering Graduate Program, University of Calgary, Calgary, Alberta, T2N 4N1, Canada; Department of Radiology, Faculty of Medicine, University of Calgary, Calgary, Alberta, T2N 4N1, Canada; Hotchkiss Brain Institute, University of Calgary, Alberta, T2N 4N1, Canada; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, T2N 4N1, Canada.
Qiong ZhangDepartment of Radiology, Faculty of Medicine, University of Calgary, Calgary, Alberta, T2N 4N1, Canada; Hotchkiss Brain Institute, University of Calgary, Alberta, T2N 4N1, Canada; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, T2N 4N1, Canada.
Ying WuDepartment of Radiology, Faculty of Medicine, University of Calgary, Calgary, Alberta, T2N 4N1, Canada; Hotchkiss Brain Institute, University of Calgary, Alberta, T2N 4N1, Canada; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, T2N 4N1, Canada.
Thomas W JohnsonBiomedical Engineering Graduate Program, University of Calgary, Calgary, Alberta, T2N 4N1, Canada; Department of Radiology, Faculty of Medicine, University of Calgary, Calgary, Alberta, T2N 4N1, Canada; Hotchkiss Brain Institute, University of Calgary, Alberta, T2N 4N1, Canada; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, T2N 4N1, Canada.
Jeff F DunnDepartment of Radiology, Faculty of Medicine, University of Calgary, Calgary, Alberta, T2N 4N1, Canada; Hotchkiss Brain Institute, University of Calgary, Alberta, T2N 4N1, Canada; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, T2N 4N1, Canada. Electronic address: dunnj@ucalgary.ca.
University of Calgary · CA

Funding

Development and validation of a multimodal MRI/near-infrared spectroscopysystem to study brain oxidative metabolism in mouse models of neurologicaldiseaseR21EB021397 · NIBIB · UNIVERSITY OF CALGARY · PI DUNN, JEFFREY FRANK · 2016 to 2017
$295k
NIBIB NIH HHS R21 EB021397
6 · The paper itself

Abstract

Non-invasive quantitative imaging of cerebral oxygen metabolism (CMRO

Indexed as

AnimalsCerebral CortexCerebrovascular CirculationGray MatterHypothermiaMagnetic Resonance ImagingMaleMiceMultimodal ImagingOxygenRatsSpectroscopy, Near-InfraredOxygenArterial spin labelingCerebral blood flow (CBF)Cerebral metabolic rate for oxygen (CMRO(2))HypothermiaMRINear-infrared spectroscopy (NIRS)

Identifiers

PMID31669409
PMCPMC6983321
OpenAlexW2981806491

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.