Evidence map›Paper›PMID 31668661›Full record

ReviewAdvances in biological regulation2020

Induction of membrane curvature by proteins involved in Golgi trafficking.

Stefanie L Makowski, Ramya S Kuna, Seth J Field

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advances in biological regulation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Golgi Drivers of Cancer.Sub-cellular biochemistry · 2026
    Review
  2. Article
  3. Regulation of yeast polarized exocytosis by phosphoinositide lipids.Cellular and molecular life sciences : CMLS · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stefanie L MakowskiDepartment of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA, 92093, USA.
Ramya S KunaDepartment of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA, 92093, USA.
Seth J FieldDepartment of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA, 92093, USA. Electronic address: sjfield@ucsd.edu.
University of California, San Diego · US

Funding

EXPERIMENTAL ENDOCRINOLOGY AND METABOLISMT32DK007044 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Amit Majithia · 1986 to 2026
$4.6M
GOLPH3 Pathway Regulation of Golgi Structure and FunctionR01GM120055 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELD, SETH J · 2016 to 2019
$1.3M
High Throughput Screen to Identify Inhibitors of the Golgi GOLPH3 PathwayR01CA201303 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELD, SETH J · 2016 to 2018
$1.2M
NCI NIH HHS R01 CA201303NIDDK NIH HHS T32 DK007044NIGMS NIH HHS R01 GM120055
6 · The paper itself

Abstract

The Golgi apparatus serves a key role in processing and sorting lipids and proteins for delivery to their final cellular destinations. Vesicle exit from the Golgi initiates with directional deformation of the lipid bilayer to produce a bulge. Several mechanisms have been described by which lipids and proteins can induce directional membrane curvature to promote vesicle budding. Here we review some of the mechanisms implicated in inducing membrane curvature at the Golgi to promote vesicular trafficking to various cellular destinations.

Indexed as

Golgi ApparatusHumansLipid BilayersMembrane ProteinsPhosphatidylinositol PhosphatesProtein TransportTransport VesiclesLipid BilayersMembrane ProteinsPhosphatidylinositol PhosphatesGolgiGOLPH3Membrane curvaturePhosphoinositidesTraffickingVesicle budding

Identifiers

PMID31668661
PMCPMC7056495
OpenAlexW2980728230

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.