ArticleJournal of biomedical optics2019
Contribution of speckle noise in near-infrared spectroscopy measurements.
Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- 1060 nm interferometric near-infrared spectroscopy.Optics letters · 2025Article
- Finite Element Modeling of Abdominal Near-Infrared Spectroscopy for Infant Splanchnic Oximetry.International journal for numerical methods in biomedical engineering · 2025Article
- Multivariate Kalman filter regression of confounding physiological signals for real-time classification of fNIRS data.Neurophotonics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Near-infrared spectroscopy (NIRS) is widely used in biomedical optics with applications ranging from basic science, such as in functional neuroimaging, to clinical, as in pulse oximetry. Despite the relatively low absorption of tissue in the near-infrared, there is still a significant amount of optical attenuation produced by the highly scattering nature of tissue. Because of this, designers of NIRS systems have to balance source optical power and source–detector separation to maximize the signal-to-noise ratio (SNR). However, theoretical estimations of SNR neglect the effects of speckle. Speckle manifests as fluctuations of the optical power received at the detector. These fluctuations are caused by interference of the multiple random paths taken by photons in tissue. We present a model for the NIRS SNR that includes the effects of speckle. We performed experimental validations with a NIRS system to show that it agrees with our model. Additionally, we performed computer simulations based on the model to estimate the contribution of speckle noise for different collection areas and source–detector separations. We show that at short source–detector separation, speckle contributes most of the noise when using long coherence length sources. Considering this additional noise is especially important for hybrid applications that use NIRS and speckle contrast simultaneously, such as in diffuse correlation spectroscopy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.