SynthesisJournal of diabetes investigation2020
Association between the ferritin level and risk of gestational diabetes mellitus: A meta-analysis of observational studies.
Synthesis in Journal of diabetes investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Relationship of Circulating Copper Level with Gestational Diabetes Mellitus: a Meta-Analysis and Systemic Review.Biological trace element research · 2021Pooled it
- Association between the ferritin level and risk of gestational diabetes mellitus: A meta-analysis of observational studies.Journal of diabetes investigation · 2020Pooled it
- Association of iron status during early pregnancy and the risk of gestational diabetes: a retrospective cohort study in Shanghai.BMJ open · 2026Article
- Associations of maternal hemoglobin and its changes with gestational diabetes mellitus: a prospective cohort study.Nutrition journal · 2026Article
- Association Between Longitudinal Serum Ferritin and Gestational Diabetes Mellitus - Beijing, Shanxi, and Shandong PLADs, China, 2021-2024.China CDC weekly · 2026Article
- Metformin and Placental Ferroptosis in Gestational Diabetes: A Mechanistic Study.Journal of diabetes research · 2026Article
- Maternal systemic iron homeostasis in diabetes-in-pregnancy: A cross-sectional analytical study from a tertiary health care centre of South India.Saudi medical journal · 2025Article
- Serum ferritin levels and risk of gestational diabetes mellitus: A cohort study.Scientific reports · 2025Article
- The association between serum ferritin levels and the risk of gestational diabetes mellitus: a prospective cohort study.BMC pregnancy and childbirth · 2025Article
- Maternal Iron Levels and Association With Gestational Diabetes: A Systematic Review and Meta-Analysis.Journal of nutrition and metabolism · 2025Review
- Iron Deficiency Anaemia in Pregnancy: A Narrative Review from a Clinical Perspective.Diagnostics (Basel, Switzerland) · 2024Review
- The Role of Maternal Serum Ferritin in Gestational Diabetes Mellitus in Southeast Asia.Cureus · 2024Article
- The mediation effect of asprosin on the association between ambient air pollution and diabetes mellitus in the elderly population in Taiyuan, China.Environmental science and pollution research international · 2024Article
- Ferritin and iron supplements in gestational diabetes mellitus: less or more?European journal of nutrition · 2024Review
- Insights into the pathogenesis of gestational and hepatic diseases: the impact of ferroptosis.Frontiers in cell and developmental biology · 2024Review
- Maternal hemoglobin change from early pregnancy to second trimester is associated with risk of gestational diabetes mellitus: a retrospective cohort study.Frontiers in nutrition · 2023Article
- Ferroptosis and its potential role in gestational diabetes mellitus: updated evidence from pathogenesis to therapy.Frontiers in endocrinology · 2023Article
- Maternal first trimester iron status and its association with obstetric and perinatal outcomes.Archives of gynecology and obstetrics · 2022Article
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
AIMS/
introductionThe relationship between ferritin and the risk of gestational diabetes mellitus (GDM) has not been established. Thus, we carried out a meta-analysis based on the current literature. MATERIALS AND
methodsWe searched relevant databases on Embase, PubMed, Cochrane Library and Web of Science before 10 May 2019 to determine the relationship between ferritin and the risk of GDM. The relative risks and 95% confidence intervals of GDM risk were summarized using a random effects model. Studies using categories of ferritin as exposure were combined by dose-response analysis. We carried out both linear and non-linear trends. We also carried out subgroup analysis, whether or not the studies adjusted for potential confounders, and meta-regression analysis to explore the source of heterogeneity. Sensitivity analysis was carried out to explore the robustness of the meta-analysis results.
resultsA total of 10 studies involving 4,690 participants were identified. The summary relative risk comparing persons with the highest concentration categories of ferritin with the lowest concentration categories of ferritin was 1.87 (95% confidence interval 1.50-2.34; I
conclusionsThe findings from this meta-analysis suggest that increased ferritin levels are associated with an increased risk of GDM; however, we require further prospective cohort studies to confirm the results, especially the dose-response relationship between ferritin and GDM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.