Evidence map›Paper›PMID 31667977›Full record

Trial reportEuropean journal of heart failure2020

Impact of pulmonary disease on the prognosis in heart failure with preserved ejection fraction: the TOPCAT trial.

Sergio H R Ramalho, Brian L Claggett, Nancy K Sweitzer, James C Fang, Sanjiv J Shah, Inder S Anand, Bertram Pitt, Eldrin F Lewis, Marc A Pfeffer, Scott D Solomon and 1 more

Open access · bronzeAbstract readClinical TrialLetter
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Review
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Sergio H R RamalhoDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Brian L ClaggettDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Nancy K SweitzerUniversity of Arizona, Tucson, AZ, USA.
James C FangUniversity of Utah, Salt Lake City, UT, USA.
Sanjiv J ShahNorthwestern University, Chicago, IL, USA.
Inder S AnandUniversity of Minnesota, Minneapolis, MN, USA.
Bertram PittUniversity of Michigan, Ann Arbor, MI, USA.
Eldrin F LewisDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Marc A PfefferDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Scott D SolomonDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Amil M ShahDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Brigham and Women's Hospital · USNorthwestern University · USUniversidade de Brasília · BRUniversity of Arizona · USUniversity of Michigan–Ann Arbor · USUniversity of Minnesota · USUniversity of Utah · US

Funding

Mapping the Progression to HFpEF in the Elderly through Longitudinal Changes in Cardiac FunctionR01HL135008 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI Amil M Shah · 2017 to 2026
$11.5M
Quantifying cardiac structure and function to define the progression to hear failure in African AmericansR01HL143224 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAH, AMIL M · 2018 to 2021
$3.4M
Systolic & diastolic dysfunction in heart failure and preserved ejection fractionK08HL116792 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SHAH, AMIL M · 2013 to 2017
$735k
Mentoring patient-oriented research in deep phenotyping of cardiac function for heart failure preventionK24HL152008 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SHAH, AMIL M · 2020 to 2024
$608k
HHSNHLBI NIH HHS HHSN268200425207CNHLBI NIH HHS K08 HL116792NHLBI NIH HHS K24 HL152008NHLBI NIH HHS R01 HL135008NHLBI NIH HHS R01 HL143224
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heart FailureLung DiseasesHumansMineralocorticoid Receptor AntagonistsPrognosisSpironolactoneStroke VolumeMineralocorticoid Receptor AntagonistsSpironolactone

Identifiers

PMID31667977
PMCPMC12711424
OpenAlexW2983355200

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.