Evidence map›Paper›PMID 31667746›Full record

ArticleJournal of general internal medicine2020

Mortality Among Veterans with Major Mental Illnesses Seen in Primary Care: Results of a National Study of Veteran Deaths.

Ranak B Trivedi, Edward P Post, Rebecca Piegari, Joseph Simonetti, Edward J Boyko, Steven M Asch, Alaina Mori, Bruce A Arnow, Stephan D Fihn, Karin M Nelson and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Ranak B TrivediCenter for Innovation to Implementation, VA Palo Alto Health Care System 795 Willow Rd 152-MPD, Menlo Park, 94025, CA, USA. ranak.trivedi@va.gov.
Edward P PostCenter for Clinical Management Research, VA Ann Arbor Health Care System, Ann Arbor, MI, USA.
Rebecca PiegariOffice of Clinical Systems Development and Evaluation, Canandaigua VA Medical Center, Canandaigua, NY, USA.
Joseph SimonettiRocky Mountain Mental Illness Research, Education and Clinical Center, Rocky Mountain Regional VA Medical Center, Aurora, CO, USA.
Edward J BoykoSeattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Tacoma, WA, USA.
Steven M AschCenter for Innovation to Implementation, VA Palo Alto Health Care System 795 Willow Rd 152-MPD, Menlo Park, 94025, CA, USA.
Alaina MoriPrimary Care Analytics Team, VA Puget Sound Health Care System, Tacoma, WA, USA.
Bruce A ArnowDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Stephan D FihnGeneral Internal Medicine, University of Washington, Seattle, WA, USA.
Karin M NelsonPrimary Care Analytics Team, VA Puget Sound Health Care System, Tacoma, WA, USA.
Charles MaynardDenver-Seattle Center of Innovation for Veteran-Centered and Value-Driven Care, Seattle, WA, USA.
Center for Innovation · USUniversity of Washington · USVA Puget Sound Health Care System · USCanandaigua VA Medical Center · USStanford University · USUniversity of Michigan–Ann Arbor · USVA Palo Alto Health Care System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPremature mortality observed among the mentally ill is largely attributable to chronic illnesses. Veterans seen within Veterans Affairs (VA) have a higher prevalence of mental illness than the general population but there is limited investigation into the common causes of death of Veterans with mental illnesses.

objectiveTo characterize the life expectancy of mentally ill Veterans seen in VA primary care, and to determine the most death rates of combinations of mental illnesses.

designRetrospective cohort study of decedents. SETTING/

participantsVeterans seen in VA primary care clinics between 2000 and 2011 were included. Records from the VA Corporate Data Warehouse (CDW) were merged with death information from the National Death Index. MAIN MEASURES: Mental illnesses were determined using ICD9 codes. Direct standardization methods were used to calculate age-adjusted gender and cause-specific death rates per 1000 deaths for patients with and without depression, anxiety, post-traumatic stress disorder (PTSD), substance use disorder (SUD), serious mental illness (SMI), and combinations of those diagnoses. KEY

resultsOf the 1,763,982 death records for Veterans with 1 + primary care visit, 556,489 had at least one mental illness. Heart disease and cancer were the two leading causes of death among Veterans with or without a mental illness, accounting for approximately 1 in 4 deaths. Those with SUD (n = 204,950) had the lowest mean age at time of death (64 ± 12 years). Among men, the death rates were as follows: SUD (55.9/1000); anxiety (49.1/1000); depression (45.1/1000); SMI (40.3/1000); and PTSD (26.2/1000). Among women, death rates were as follows: SUD (55.8/1000); anxiety (36.7/1000); depression (45.1/1000); SMI (32.6/1000); and PTSD (23.1/1000 deaths). Compared to men (10.8/1000) and women (8.7/1000) without a mental illness, these rates were multiple-fold higher in men and in women with a mental illness. A greater number of mental illness diagnoses was associated with higher death rates among men and women (p < 0.0001).

conclusionsVeterans with mental illnesses, particularly those with SUD, and those with multiple diagnoses, had shorter life expectancy than those without a mental illness. Future studies should examine both patient and systemic sources of disparities in providing chronic illness care to Veterans with a mental illness.

Indexed as

Mental DisordersSubstance-Related DisordersVeteransAnxiety DisordersFemaleHumansMalePrimary Health CareRetrospective StudiesUnited StatesUnited States Department of Veterans Affairscause of deathmental disordersprimary care medical homeVeterans

Identifiers

PMID31667746
PMCPMC6957595
OpenAlexW2982392828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.