Evidence map›Paper›PMID 31667564›Full record

ArticleAnalytical and bioanalytical chemistry2019

Enhancing the accuracy of measurement of small molecule organic biomarkers.

Tang Lin Teo, Katrice A Lippa, Lindsey Mackay, Sharon Yong, Qinde Liu, Johanna E Camara, Vincent Delatour, Tong Kooi Lee, Béatrice Lalere, Gavin O' Connor and 9 more

Abstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Tang Lin TeoChemical Metrology Laboratory, Applied Sciences Group, Health Science Authority (HSA), 1 Science Park Road, The Capricorn, Science Park II, Singapore, 117528, Singapore. Teo_Tang_Lin@hsa.gov.sg.
Katrice A LippaNational Institute of Standards and Technology (NIST), 100 Bureau Drive, Gaithersburg, MD, 20899, USA.
Lindsey MackayNational Measurement Institute Australia (NMIA), 105 Delhi Rd, North Ryde, NSW, 2113, Australia.
Sharon YongChemical Metrology Laboratory, Applied Sciences Group, Health Science Authority (HSA), 1 Science Park Road, The Capricorn, Science Park II, Singapore, 117528, Singapore.
Qinde LiuChemical Metrology Laboratory, Applied Sciences Group, Health Science Authority (HSA), 1 Science Park Road, The Capricorn, Science Park II, Singapore, 117528, Singapore.
Johanna E CamaraNational Institute of Standards and Technology (NIST), 100 Bureau Drive, Gaithersburg, MD, 20899, USA.
Vincent DelatourLaboratoire National De Métrologie Et D'essais (LNE), 1 Rue Gaston Boissier, 75015, Paris, France.
Tong Kooi LeeChemical Metrology Laboratory, Applied Sciences Group, Health Science Authority (HSA), 1 Science Park Road, The Capricorn, Science Park II, Singapore, 117528, Singapore.
Béatrice LalereLaboratoire National De Métrologie Et D'essais (LNE), 1 Rue Gaston Boissier, 75015, Paris, France.
Gavin O' ConnorPhysikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116, Braunschweig, Germany.
André HenrionPhysikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116, Braunschweig, Germany.
Megumi KatoNational Metrology Institute of Japan (NMIJ), National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba, Ibaraki, 305-8563, Japan.
Masahiko NumataNational Metrology Institute of Japan (NMIJ), National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba, Ibaraki, 305-8563, Japan.
Ha-Jeong KwonKorea Research Institute of Standards and Science (KRISS), 267 Gajeong-ro, Yuseong-gu, Daejeon, 34113, Republic of Korea.
Ji-Seon JeongKorea Research Institute of Standards and Science (KRISS), 267 Gajeong-ro, Yuseong-gu, Daejeon, 34113, Republic of Korea.
Bei XuNational Institute of Metrology, China (NIM), No.18, Bei San Huang Dong Lu, Chaoyang District, Beijing, 100029, China.
Dewei SongNational Institute of Metrology, China (NIM), No.18, Bei San Huang Dong Lu, Chaoyang District, Beijing, 100029, China.
Jintana NammoonnoyNational Institute of Metrology, Thailand (NIMT), Technopolis Campus, 3/4-5 Moo 3, Klong 5, Klong Luang, Pathumthani, 12120, Thailand.
Wagner WollingerInstituto Nacional de Metrologia, Qualidade e Tecnologia (INMETRO), 50 N Sra das Gracas, Duque de Caxias, Rio de Janeiro, 25250-020, Brazil.

Funding

Intramural NIST DOC 9999-NIST
6 · The paper itself

Abstract

Over two decades, the Organic Analysis Working Group (OAWG) of the Consultative Committee for Amount of Substance: Metrology in Chemistry and Biology (CCQM) has organized a number of comparisons for clinically relevant small molecule organic biomarkers. The aim of the OAWG community is to be part of the coordinated international movement towards accuracy and comparability of clinical measurements that will, in turn, minimize the wastage of repeat testing and unnecessary therapy to create a sustainable healthcare industry. International and regional directives/requirements on metrological traceability of calibrators and control materials are in place. Metrology institutes worldwide maintain infrastructure for the practical realization of metrological traceability and demonstrate the equivalence of their measurement capabilities through participation in key comparisons organized under the auspices of the CCQM. These institutes provide certified reference materials, as well as other dedicated value-assignment services benefiting the in-vitro diagnostic (IVD) industry, reference (calibration) laboratories and the clinical chemistry laboratories. The roles of these services in supporting national, regional, and international activities to ensure the metrological traceability of clinical chemistry measurements are described. Graphical abstract.

Indexed as

BiomarkersCalibrationClinical Chemistry TestsHumansIn Vitro TechniquesOrganic ChemicalsReference StandardsReproducibility of ResultsSmall Molecule LibrariesBiomarkersOrganic ChemicalsSmall Molecule LibrariesBiomarkerCertified reference materials (CRMs)Clinical measurementsExternal quality assessment schemes (EQAS)Metrological traceabilityPilot studies and key comparisons

Identifiers

PMID31667564
PMCPMC11087866

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.