ArticleCerebral cortex (New York, N.Y. : 1991)2020
Cognitive Enhancement via Network-Targeted Cortico-cortical Associative Brain Stimulation.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Relational Integration Training Modulated the Frontoparietal Network for Fluid Intelligence: An EEG Microstates Study.Brain topography · 2025Trial
- Trial
- Optimal stochastic tracking control for brain network dynamics.Communications biology · 2025Article
- Article
- Precision Network Modeling of Transcranial Magnetic Stimulation Across Individuals Suggests Therapeutic Targets and Potential for Improvement.Human brain mapping · 2025Article
- Cortico-Cortical Paired Associative Stimulation (ccPAS) in Ageing and Alzheimer's Disease: A Quali-Quantitative Approach to Potential Therapeutic Mechanisms and Applications.Brain sciences · 2025Article
- Precision Network Modeling of Transcranial Magnetic Stimulation Across Individuals Suggests Therapeutic Targets and Potential for Improvement.medRxiv : the preprint server for health sciences · 2024Article
- Controlling target brain regions by optimal selection of input nodes.PLoS computational biology · 2024Article
- Reorganization of structural connectivity in the brain supports preservation of cognitive ability in healthy aging.Network neuroscience (Cambridge, Mass.) · 2024Article
- Advocating for neurodata privacy and neurotechnology regulation.Nature protocols · 2023Review
- Neural Contributions to Reduced Fluid Intelligence across the Adult Lifespan.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Gradual enhancement of corticomotor excitability during cortico-cortical paired associative stimulation.Scientific reports · 2022Article
- Interventional neurorehabilitation for promoting functional recovery post-craniotomy: a proof-of-concept.Scientific reports · 2022Article
- Comments on "Cortico-cortical connectivity: the road from basic neurophysiological interactions to therapeutic applications" (Koch, Exp Brain Res., 2020).Experimental brain research · 2021Article
- Personalised, image-guided, noninvasive brain stimulation in gliomas: Rationale, challenges and opportunities.EBioMedicine · 2021Review
- Response letter to comments on "Cortico-cortical connectivity: the road from basic neurophysiological interactions to therapeutic applications" by Zibman and Zangen.Experimental brain research · 2021Article
- Network-level macroscale structural connectivity predicts propagation of transcranial magnetic stimulation.NeuroImage · 2021Article
- Modulating Frontal Networks' Timing-Dependent-Like Plasticity WithFrontiers in human neuroscience · 2021Review
- Functional Imaging to Guide Network-Based TMS Treatments: Toward a Tailored Medicine Approach in Alzheimer's Disease.Frontiers in neuroscience · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
Abstract
Fluid intelligence (gf) represents a crucial component of human cognition, as it correlates with academic achievement, successful aging, and longevity. However, it has strong resilience against enhancement interventions, making the identification of gf enhancement approaches a key unmet goal of cognitive neuroscience. Here, we applied a spike-timing-dependent plasticity (STDP)-inducing brain stimulation protocol, named cortico-cortical paired associative stimulation (cc-PAS), to modulate gf in 29 healthy young subjects (13 females-mean ± standard deviation, 25.43 years ± 3.69), based on dual-coil transcranial magnetic stimulation (TMS). Pairs of neuronavigated TMS pulses (10-ms interval) were delivered over two frontoparietal nodes of the gf network, based on individual functional magnetic resonance imaging data and in accordance with cognitive models of information processing across the prefrontal and parietal lobe. cc-PAS enhanced accuracy at gf tasks, with parieto-frontal and fronto-parietal stimulation significantly increasing logical and relational reasoning, respectively. Results suggest the possibility of using SPTD-inducing TMS protocols to causally validate cognitive models by selectively engaging relevant networks and manipulating inter-regional temporal dynamics supporting specific cognitive functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.