ArticleCerebral cortex (New York, N.Y. : 1991)2020
Cellular and Widefield Imaging of Sound Frequency Organization in Primary and Higher Order Fields of the Mouse Auditory Cortex.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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72 citing papers in PubMed.
- A cortical output channel for perceptual categorization.Science advances · 2026Article
- Neural mechanisms of fear memory precision and generalization: from auditory cortex to amygdala.Translational psychiatry · 2026Review
- Transcranial Calcium Macro-Imaging From the Auditory Cortex of Thy1-Cre-Driven GCaMP8 Transgenic Rats.Neuropsychopharmacology reports · 2026Article
- Cortical representation of pitch perception in mice.Communications biology · 2026Article
- Altered folate metabolism disrupts auditory function from neonatal vocalizations to adult perceptual precision.Journal of neurodevelopmental disorders · 2026Article
- Layer 5 and 6b extratelencephalic neurons encode distinct sound features in auditory cortex.bioRxiv : the preprint server for biology · 2026Article
- An intralayer microcircuit in the temporal association cortex underlies sensory-induced escape in mice.Nature communications · 2026Article
- Thalamic reticular neurons provide cell type-specific modulation of sound processing in the auditory thalamus.PLoS biology · 2026Article
- Large cranial windows distort sensory maps and degrade feature integration in higher-order cortex.bioRxiv : the preprint server for biology · 2026Article
- The representation of omitted sounds in the mouse auditory cortex.Nature communications · 2026Article
- Tonotopic organization in the basal region of the ventromedial nucleus of the thalamus revealed by fiber photometry recording.Neurophotonics · 2026Article
- Differential Myeloarchitecture of Subfields of the Mammalian Auditory Cortex: A Comparative Approach.Brain, behavior and evolution · 2026Review
- A Protocol for Microprism-Based Two-Photon Imaging Of The Lateral Cortex In The Mouse Inferior Colliculus.Current protocols · 2026Article
- Orthogonal spectral and temporal envelope representation during the onset phase in auditory cortex.iScience · 2025Article
- Article
- Sound feature representations decorrelate across the mouse auditory pathway.PLoS biology · 2025Article
- Cell type-specific plasticity in synaptic, intrinsic, and sound response properties of deep-layer cortical neurons after noise trauma.Science advances · 2025Article
- Cortical Representation of Pitch Perception in Mice.bioRxiv : the preprint server for biology · 2025Article
- Noncanonical short-latency auditory pathway directly activates deep cortical layers.Nature communications · 2025Article
- Article
12 more citing papers are in PubMed but not listed here.
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7 authors.
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Abstract
The mouse auditory cortex (ACtx) contains two core fields-primary auditory cortex (A1) and anterior auditory field (AAF)-arranged in a mirror reversal tonotopic gradient. The best frequency (BF) organization and naming scheme for additional higher order fields remain a matter of debate, as does the correspondence between smoothly varying global tonotopy and heterogeneity in local cellular tuning. Here, we performed chronic widefield and two-photon calcium imaging from the ACtx of awake Thy1-GCaMP6s reporter mice. Data-driven parcellation of widefield maps identified five fields, including a previously unidentified area at the ventral posterior extreme of the ACtx (VPAF) and a tonotopically organized suprarhinal auditory field (SRAF) that extended laterally as far as ectorhinal cortex. Widefield maps were stable over time, where single pixel BFs fluctuated by less than 0.5 octaves throughout a 1-month imaging period. After accounting for neuropil signal and frequency tuning strength, BF organization in neighboring layer 2/3 neurons was intermediate to the heterogeneous salt and pepper organization and the highly precise local organization that have each been described in prior studies. Multiscale imaging data suggest there is no ultrasonic field or secondary auditory cortex in the mouse. Instead, VPAF and a dorsal posterior (DP) field emerged as the strongest candidates for higher order auditory areas.
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