Evidence map›Paper›PMID 31667151›Full record

ArticleAnnals of cardiothoracic surgery2019

Management of malperfusion syndrome in acute type A aortic intramural hematoma.

Elizabeth L Norton, David M Williams, Karen M Kim, Xiaoting Wu, Minhaj S Khaja, Himanshu J Patel, G Michael Deeb, Bo Yang

Open access · diamondAbstract read
In one paragraph

Article in Annals of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Successful Primary PCI in Stanford Type A Aortic Dissection Complicated by Inferior ST-Elevation Myocardial Infarction: A Case in a Facility with No Surgical Backup.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Elizabeth L NortonCreighton University School of Medicine, Omaha, NE, USA.
David M WilliamsDepartment of Radiologyy, Michigan Medicine, Ann Arbor, MI, USA.
Karen M KimDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Xiaoting WuDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Minhaj S KhajaDepartment of Radiologyy, Michigan Medicine, Ann Arbor, MI, USA.
Himanshu J PatelDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, MI, USA.
G Michael DeebDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Bo YangDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, MI, USA.
Michigan Medicine · USCreighton University · US

Funding

Define the mechanisms of aortopathy in bicuspid aortic valve patientsR01HL141891 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YANG, BO · 2018 to 2022
$3.5M
Effect of mutations in the TGF-beta pathway genes on smooth muscle cell differentiation using patient derived iPSCs.K08HL130614 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YANG, BO · 2016 to 2020
$848k
NHLBI NIH HHS K08 HL130614NHLBI NIH HHS R01 HL141891
6 · The paper itself

Abstract

backgroundWe report the outcomes of acute type A aortic intramural hematoma (ATAAIMH) with malperfusion treated with endovascular intervention and delayed open aortic repair.

methodsBetween April 1998 and April 2018, 644 patients were treated at our institution with an acute type A aortic dissection (ATAAD) or ATAAIMH, 82 (13%) had intramural hematomas (IMHs) including 12 (15%) with malperfusion syndrome (MPS) and 70 (85%) without MPS (no MPS). Data was obtained through medical record review, the Society of Thoracic Surgeons data elements, and the National Death Index database.

resultsBoth MPS and No MPS groups had similar comorbidities including coronary artery disease, hypertension, diabetes, and peripheral vascular disease; however, those with MPS were sicker on admission with higher rates of acute renal failure (50%

conclusionsATAAIMH with MPS can be effectively managed with upfront endovascular fenestration/stenting followed by delayed aortic repair.

Indexed as

Aortic dissectionaortic intramural hematoma (IMHs)malperfusion syndrome (MPS)

Identifiers

PMID31667151
PMCPMC6785498
OpenAlexW2963475239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.