ArticlePeerJ2019
Presence of Papillomavirus DNA sequences in the canine transmissible venereal tumor (CTVT).
Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Epidemiological determinants of canine transmissible venereal tumor in Northeastern Brazil: Insights from a retrospective case-control analysis.Veterinary and animal science · 2026Article
- Molecular investigation of the role of papillomaviruses in the etiology of transmissible venereal tumors (TVT) in dogs.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Canine Transmissible Venereal Tumor: Anatomical Locations, Chemotherapy Response, and Epidemiological Aspects at a Veterinary Teaching Hospital in Brazil (2012-2022).Animals : an open access journal from MDPI · 2025Article
- A Universal and Quantitative PCR Strategy for Detection and Epidemiologic Analysis of Canine Papillomavirus (CPV).International journal of molecular sciences · 2025Article
- Canine papillomavirus: status of diagnostic methods and vaccine innovations.Virology journal · 2025Review
- New insights into Canis familiaris papillomaviruses genetics and biology: Is the genetic characterization of CPV types and their variants an important clinical issue?Genetics and molecular biology · 2022Article
- HPV oral and oropharynx infection dynamics in young population.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- A First NGS Investigation Suggests No Association Between Viruses and Canine Cancers.Frontiers in veterinary science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe canine transmissible venereal tumor (CTVT) or Sticker's sarcoma is a neoplastic disease affecting dogs. This disease is presented as a tumoral mass in the genital organs of both, male and female individuals. Up to date, there is no clear evidence indicating a viral agent as the causative mediator for CTVT development. PURPOSE: The present work aims to analyze 21 samples from canines with CTVT for molecular identification of Papillomavirus DNA sequences. In addition, microbiological analysis, cytologic and histopathologic evaluations were also performed.
resultsAll patients showed no biochemical and microbiological alterations. Molecular analysis demonstrated the viral DNA presence in the samples using different primer sets. The MY primers amplified a 450 bp band in seven out of 21 samples (33%). The PVF and Fap64 primer set, targeting the L1 sequence of Canine Papillomavirus (CPV), showed positivity in 16 out of 21 samples (76%).
conclusionThese results support the possible causative association between CPV and CTVT; nevertheless, additional studies are required to uphold such statement. This work presents evidence indicating that a viral agent might be involved in the pathogenesis of CTVT and set the bases for a better understanding of the CTVT pathobiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.