Evidence map›Paper›PMID 31667009›Full record

ArticleCurrent ophthalmology reports2019

Adult Stem Cells, Tools for Repairing the Retina.

Afnan M Aladdad, Karl E Kador

Abstract read
In one paragraph

Article in Current ophthalmology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Retina stem cells, hopes and obstacles.World journal of stem cells · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Afnan M AladdadDepartment of Ophthalmology and Department of Biomedical Sciences, University of Missouri - Kansas City, School of Medicine, Kansas City, MO 64108.
Karl E KadorDepartment of Ophthalmology and Department of Biomedical Sciences, University of Missouri - Kansas City, School of Medicine, Kansas City, MO 64108.
University of Missouri–Kansas City · US

Funding

TISSUE ENGINEERED CELL TRANSPLANTATION FOR GLAUCOMA AND OPTIC NEUROPATHIESR01EY028946 · NEI · UNIVERSITY OF MISSOURI KANSAS CITY · PI KADOR, KARL ERICH · 2018 to 2022
$1.9M
NEI NIH HHS R01 EY028946
6 · The paper itself

Abstract

purposeRetinal degenerative diseases lead to the death of retinal neurons causing visual impairment and blindness. In lower order vertebrates, the retina and its surrounding tissue contain stem cell niches capable of regenerating damaged tissue. Here we examine these niches and review their capacity to be used as retinal stem/progenitor cells (RSC/RPCs) for retinal repair. RECENT

findingsExogenous factors can control the SUMMARY: Whereas cell transplantation still holds potential for retinal repair, activation of the dormant native regeneration process may lead to a more successful process including greater integration efficiency and proper synaptic targeting.

Indexed as

retinal adult stem cellsretinal regenerationretinal stem cells niche

Identifiers

PMID31667009
PMCPMC6821446
OpenAlexW2913554377

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.