Evidence map›Paper›PMID 31666991›Full record

ArticleNPJ vaccines2019

An oral alpha-galactosylceramide adjuvanted

Stephanie Longet, Aine Abautret-Daly, Christopher J H Davitt, Craig P McEntee, Vincenzo Aversa, Monica Rosa, Ivan S Coulter, Jan Holmgren, Sukanya Raghavan, Ed C Lavelle

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Bibliometric analysis ofFrontiers in microbiology · 2025
    Pooled it
  2. Article
  3. Review
  4. Adjuvants forVirulence · 2024
    Review
  5. Developing a potent vaccine againstExpert reviews in molecular medicine · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Solid Lipid Nanoparticles Delivering a DNA Vaccine EncodingInternational journal of molecular sciences · 2024
    Article
  10. C5aRNPJ vaccines · 2023
    Article
  11. Review
  12. Current Progress and Challenges in the Study of Adjuvants for Oral Vaccines.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  13. How Long Will It Take to Launch an EffectiveInfection and drug resistance · 2023
    Review
  14. Review
  15. Mucosal vaccines - fortifying the frontiers.Nature reviews. Immunology · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Outer Membrane Vesicles ofFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Stephanie Longet *1Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 R590 Ireland.
Aine Abautret-Daly *1Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 R590 Ireland.
Christopher J H Davitt1Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 R590 Ireland.
Craig P McEntee1Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 R590 Ireland.ORCID 0000-0002-4762-7607
Vincenzo Aversa2Sublimity Therapeutics Limited, Dublin City University, Alpha Innovation Campus, Old Finglas Road, Dublin, D11 KXN4 Ireland.
Monica Rosa2Sublimity Therapeutics Limited, Dublin City University, Alpha Innovation Campus, Old Finglas Road, Dublin, D11 KXN4 Ireland.
Ivan S Coulter2Sublimity Therapeutics Limited, Dublin City University, Alpha Innovation Campus, Old Finglas Road, Dublin, D11 KXN4 Ireland.
Jan Holmgren3University of Gothenburg Vaccine Research Institute, Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Box 435, 405 30 Gothenburg, Sweden.
Sukanya Raghavan *3University of Gothenburg Vaccine Research Institute, Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Box 435, 405 30 Gothenburg, Sweden.
Ed C Lavelle *1Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 R590 Ireland.ORCID 0000-0002-3167-1080
Trinity College Dublin · IEDublin City University · IEInstitute for Biomedicine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Preclinical researchVaccines

Identifiers

PMID31666991
PMCPMC6814776
OpenAlexW2981690611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.