Evidence map›Paper›PMID 31666940›Full record

ReviewCell regeneration (London, England)2019

Methods and applications of CRISPR/Cas system for genome editing in stem cells.

Guang Yang, Xingxu Huang

Open access · diamondAbstract readReview
In one paragraph

Review in Cell regeneration (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Frontiers in genome editing · 2022
    Article
  7. CRISPR: The Multidrug Resistance Endgame?Molecular biotechnology · 2021
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Various Aspects of a Gene Editing System-CRISPR-Cas9.International journal of molecular sciences · 2020
    Review
  13. Welcome to Cell Regeneration.Cell regeneration (London, England) · 2020
    Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Guang YangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Xingxu HuangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
ShanghaiTech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome editing technology holds great promise for genome manipulation and gene therapy. While widespread utilization, genome editing has been used to unravel the roles of specific genes in differentiation and pluripotency of stem cells, and reinforce the stem cell-based applications. In this review, we summarize the advances of genome editing technology, as well as the derivative technologies from CRISPR/Cas system, which show tremendous potential in various fields. We also highlight the key findings in the studies of stem cells and regeneration by genome editing technology.

Indexed as

CRISPR/Cas9Gene therapyGenome editingStem cell

Identifiers

PMID31666940
PMCPMC6806369
OpenAlexW2979876714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.