Evidence map›Paper›PMID 31666870›Full record

ReviewBeilstein journal of organic chemistry2019

Current understanding and biotechnological application of the bacterial diterpene synthase CotB2.

Ronja Driller, Daniel Garbe, Norbert Mehlmer, Monika Fuchs, Keren Raz, Dan Thomas Major, Thomas Brück, Bernhard Loll

Open access · diamondAbstract readReview
In one paragraph

Review in Beilstein journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. The initial dynamics of product release in terpene synthases-The case of CotB2.Protein science : a publication of the Protein Society · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Biosynthesis, enzymology, and future of eunicellane diterpenoids.Journal of industrial microbiology & biotechnology · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Discovery and Biosynthesis of a Structurally Dynamic Antibacterial Diterpenoid.Angewandte Chemie (International ed. in English) · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ronja DrillerInstitute of Chemistry and Biochemistry, Laboratory of Structural Biochemistry, Freie Universität Berlin, Takustr. 6, 14195 Berlin, Germany.ORCID https://orcid.org/0000-0001-8834-9087
Daniel GarbeWerner Siemens Chair of Synthetic Biotechnology, Dept. of Chemistry, Technical University of Munich (TUM), Lichtenbergstr. 4, 85748 Garching, Germany.ORCID https://orcid.org/0000-0001-7203-8751
Norbert MehlmerWerner Siemens Chair of Synthetic Biotechnology, Dept. of Chemistry, Technical University of Munich (TUM), Lichtenbergstr. 4, 85748 Garching, Germany.
Monika FuchsWerner Siemens Chair of Synthetic Biotechnology, Dept. of Chemistry, Technical University of Munich (TUM), Lichtenbergstr. 4, 85748 Garching, Germany.ORCID https://orcid.org/0000-0002-6954-2639
Keren RazDepartment of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel.
Dan Thomas MajorDepartment of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel.ORCID https://orcid.org/0000-0002-9231-0676
Thomas BrückWerner Siemens Chair of Synthetic Biotechnology, Dept. of Chemistry, Technical University of Munich (TUM), Lichtenbergstr. 4, 85748 Garching, Germany.ORCID https://orcid.org/0000-0002-2113-6957
Bernhard LollInstitute of Chemistry and Biochemistry, Laboratory of Structural Biochemistry, Freie Universität Berlin, Takustr. 6, 14195 Berlin, Germany.ORCID https://orcid.org/0000-0001-7928-4488
Siemens (Germany) · DEBar-Ilan University · ILAarhus University · DKFreie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CotB2 catalyzes the first committed step in cyclooctatin biosynthesis of the soil bacterium

Indexed as

biotechnologyCotB2crystal structurecyclooctatinditerpenereaction mechanismterpene synthase

Identifiers

PMID31666870
PMCPMC6808215
OpenAlexW2978004883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.