ArticleIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
A Wearable Fiberless Optical Sensor for Continuous Monitoring of Cerebral Blood Flow in Mice.
Article in IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Comparative validation of speckle contrast optical spectroscopy against diffuse correlation spectroscopy for monitoring human cerebral blood flow.Neurophotonics · 2026Article
- Noninvasive diffuse optical monitoring of cerebral blood flow and oxygenation responses to intermittent hypoxia in neonatal rats.Journal of biomedical optics · 2026Article
- Non-invasive real-time pulsed Doppler assessment of blood flow in mouse ophthalmic artery.Cell reports methods · 2025Article
- Article
- Wearable fiber-free optical sensor for continuous monitoring of neonatal cerebral blood flow and oxygenation.Pediatric research · 2024Article
- Compact and cost-effective laser-powered speckle contrast optical spectroscopy fiber-free device for measuring cerebral blood flow.Journal of biomedical optics · 2024Article
- Article
- Validation of the Openwater wearable optical system: cerebral hemodynamic monitoring during a breath-hold maneuver.Neurophotonics · 2024Article
- Applications of flexible electronics related to cardiocerebral vascular system.Materials today. Bio · 2023Review
- Wearable optical coherence tomography angiography probe for freely moving mice.Biomedical optics express · 2023Article
- A Wearable Fiber-Free Optical Sensor for Continuous Monitoring of Cerebral Blood Flow in Freely Behaving Mice.IEEE transactions on bio-medical engineering · 2023Article
- Recent Progress of Triboelectric Nanogenerators for Biomedical Sensors: From Design to Application.Biosensors · 2022Review
- Speckle contrast diffuse correlation tomography of cerebral blood flow in perinatal disease model of neonatal piglets.Journal of biophotonics · 2021Article
- Simultaneous measurements of tissue blood flow and oxygenation using a wearable fiber-free optical sensor.Journal of biomedical optics · 2021Article
- Noncontact optical imaging of brain hemodynamics in preterm infants: a preliminary study.Physics in medicine and biology · 2020Article
- Diffuse optical assessment of cerebral-autoregulation in older adults stratified by cerebrovascular risk.Journal of biophotonics · 2020Article
- Sensors and Systems for Physical Rehabilitation and Health Monitoring-A Review.Sensors (Basel, Switzerland) · 2020Review
- Fast pulsatile blood flow measurement in deep tissue through a multimode detection fiber.Journal of biomedical optics · 2020Article
- [Changes in three-dimensional arterial spin labeling perfusion imaging of the hippocampus in depressiveNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Continuous and longitudinal monitoring of cerebral blood flow (CBF) in animal models provides information for studying the mechanisms and interventions of various cerebral diseases. Since anesthesia may affect brain hemodynamics, researchers have been seeking wearable devices for use in conscious animals. We present a wearable diffuse speckle contrast flowmeter (DSCF) probe for monitoring CBF variations in mice. The DSCF probe consists of a small low-power near-infrared laser diode as a point source and an ultra-small low-power CMOS camera as a 2D detector array, which can be affixed on a mouse head. The movement of red blood cells in brain cortex (i.e., CBF) produces spatial fluctuations of laser speckles, which are captured by the camera. The DSCF system was calibrated using tissue phantoms and validated in a human forearm and mouse brains for continuous monitoring of blood flow increases and decreases against the established technologies. Significant correlations were observed among these measurements (R
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.