Evidence map›Paper›PMID 31666786›Full record

SynthesisEthiopian journal of health sciences2019

Prevalence of Integrons and Antibiotic Resistance Pattern in

Mehran Ghazalibina, Hamed Mortazavi, Mahtab Babadi, Mohammadreza Rahimi, Azad Khaledi, Manouchehr Teymouri, Ehsan Saburi

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Ethiopian journal of health sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. The intricacies ofFrontiers in microbiology · 2025
    Review
  2. Article
  3. Article
  4. Biofilm and Gene Expression Characteristics of the Carbapenem-Resistant Enterobacterales,International journal of environmental research and public health · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Mehran GhazalibinaDepartment of Microbiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Hamed MortazaviGeriatric Care Research Center, Department of Geriatric Nursing, School of Nursing and Midwifery, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Mahtab BabadiInfectious Diseases Research Center, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Mohammadreza RahimiInfectious Diseases Research Center, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Azad KhalediInfectious Diseases Research Center, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Manouchehr TeymouriNatural Products and Medicinal Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Ehsan SaburiImmunogenetic and Cell Culture Department, Immunology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Infectious Disease Research Institute · USIranshahr University · IRKashan University of Medical Sciences · IRMashhad University of Medical Sciences · IRNorth Khorasan University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcinetobacter baumannii is an important opportunistic nosocomial pathogen. Class 1 integrons in A. baumannii plays a significant role in antibiotic resistance. Therefore, this study aimed to investigate the prevalence of integrons and antibiotic resistance pattern in A. baumannii isolated from clinical samples of Iranian patients.

methodsThe Medical Subject Headings (MeSH) and the keywords with the help of Boolean operators ("AND" or "OR") were used alone or in combination to conduct the search. The searching process was conducted in the Web of Science, PubMed, Cochrane Library, Scopus, and Google Scholar databases and, also Iranian databases. The search was restricted to relevant English and Persian cross-sectional publications reporting the prevalence of Int1 in A. baumannii isolated from clinical samples from 1 January 2000 to 31 December 2018. The data were analyzed using Comprehensive Meta-Analysis software. Regarding the heterogeneity of studies, the random effects model was used. Cochrane Q and I

resultsFifteen studies were included in the analysis. The combined prevalence of class 1 integrons in A. baumannii was 55.2% (95% CI: 44.8-65.1). The pooled prevalence of MDR A. baumannii isolates was 68.1%. The highest resistance belonged to Aztreonam, followed by Ciprofloxacin, and Ceftazidime with a resistance rate of 97.6%, 92.8%, and 91.6%, respectively. Tobramycin was reported as an effective antibiotic.

conclusionsThe present study reported an alarmingly high prevalence of class 1 Integrons, and MDR isolates of A. baumannii recovered from clinical samples that should be considered.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialHumansIntegronsIranMicrobial Sensitivity TestsPrevalenceAnti-Bacterial AgentsAcinetobacter baumanniiIntegronsPathogenPrevalence

Identifiers

PMID31666786
PMCPMC6813273
OpenAlexW2975223141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.