Evidence map›Paper›PMID 31666363›Full record

ArticleJournal of clinical microbiology2019

Evaluation of PCR To Monitor Plasmodium falciparum Treatment Efficacy in a Nonendemicity Setting.

Claire Kamaliddin, Valentin Joste, Véronique Hubert, Eric Kendjo, Nicolas Argy, Sandrine Houze

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Persistence ofMicrobiology spectrum · 2026
    Article
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  10. Plasmodium falciparum Isolates CarryingAntimicrobial agents and chemotherapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Claire KamaliddinCentre National de Référence du Paludisme, Laboratoire de Parasitologie, Hôpital Bichat-Claude Bernard, HUPNVS, APHP, Paris, France claire.kamaliddin@gmail.com.ORCID 0000-0001-8198-6235
Valentin JosteCentre National de Référence du Paludisme, Laboratoire de Parasitologie, Hôpital Bichat-Claude Bernard, HUPNVS, APHP, Paris, France.
Véronique HubertCentre National de Référence du Paludisme, Laboratoire de Parasitologie, Hôpital Bichat-Claude Bernard, HUPNVS, APHP, Paris, France.
Eric KendjoMERIT, IRD, Université Paris, Paris, France.
Nicolas ArgyCentre National de Référence du Paludisme, Laboratoire de Parasitologie, Hôpital Bichat-Claude Bernard, HUPNVS, APHP, Paris, France.
Sandrine HouzeCentre National de Référence du Paludisme, Laboratoire de Parasitologie, Hôpital Bichat-Claude Bernard, HUPNVS, APHP, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adequate clinical and parasitological response (ACPR) after malaria treatment remains challenging to assess in settings of malaria nonendemicity. Biological evaluation of parasitological clearance relies on microscopic investigation of thick blood smears, which is a specific technique that not all diagnosis laboratories are able to perform. Rapid diagnosis tests (RDTs) and molecular biology techniques are proposed as alternatives to microscope conventional techniques; however, their performance for treatment efficacy evaluation is controversial. We present here a retrospective comparative study for RDT and PCR (nested and high-resolution-melting quantitative PCR [HRM-qPCR]) evaluation of ACPR in a nonendemicity context. Blood samples from 133 patients presenting a

Indexed as

Polymerase Chain ReactionAdultAntimalarialsFemaleHumansMalaria, FalciparumMaleMicroscopyMiddle AgedPlasmodium falciparumSensitivity and SpecificityTreatment OutcomeAntimalarialsantimalarial efficacyfollow-upHRMHRP-2imported malariaPCRPlasmodium falciparumRDT

Identifiers

PMID31666363
PMCPMC6935925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.