ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Whisking Asymmetry Signals Motor Preparation and the Behavioral State of Mice.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Orofacial Movements: Individuality and Stereotypy When Mice Move a Single Whisker to Touch.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Multimodal dataset linking wide-field calcium imaging to behavior changes in operant lever-pull task in mice.Scientific data · 2025Article
- Thalamocortical feedback selectively controls pyramidal neuron excitability.Nature communications · 2025Article
- Inferring internal states across mice and monkeys using facial features.Nature communications · 2025Article
- Bilateral integration in somatosensory cortex is controlled by behavioral relevance.Nature neuroscience · 2025Article
- Article
- The cerebellum engages multiple pre-motor pathways through a divergent-convergent architecture to shape whisker dynamics.Frontiers in neural circuits · 2025Article
- Article
- Whisker-Implanted Biomimetic Electronic Skin for Tactile Sensing and Blind Perception.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Separating cognitive and motor processes in the behaving mouse.bioRxiv : the preprint server for biology · 2024Article
- Behavioral measurements of motor readiness in mice.Current biology : CB · 2023Article
- Neurocircuitry underlying the antidepressant effect of retrograde facial botulinum toxin in mice.Cell & bioscience · 2023Article
- Behavioral measurements of motor readiness in mice.bioRxiv : the preprint server for biology · 2023Article
- Leptin deficiency-caused behavioral change - A comparative analysis using EthoVision and DeepLabCut.Frontiers in neuroscience · 2023Article
- Efficient training approaches for optimizing behavioral performance and reducing head fixation time.PloS one · 2022Article
- Anatomical description of the extratemporal facial nerve under high-definition system: a microsurgical study in rats.Acta cirurgica brasileira · 2022Article
- Article
- Body language signals for rodent social communication.Current opinion in neurobiology · 2021Review
- Systems Neuroscience of Natural Behaviors in Rodents.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Review
- Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A central function of the brain is to plan, predict, and imagine the effect of movement in a dynamically changing environment. Here we show that in mice head-fixed in a plus-maze, floating on air, and trained to pick lanes based on visual stimuli, the asymmetric movement, and position of whiskers on the two sides of the face signals whether the animal is moving, turning, expecting reward, or licking. We show that (1) whisking asymmetry is coordinated with behavioral state, and that behavioral state can be decoded and predicted based on asymmetry, (2) even in the absence of tactile input, whisker positioning and asymmetry nevertheless relate to behavioral state, and (3) movement of the nose correlates with asymmetry, indicating that facial expression of the mouse is itself correlated with behavioral state. These results indicate that the movement of whiskers, a behavior that is not instructed or necessary in the task, can inform an observer about what a mouse is doing in the maze. Thus, the position of these mobile tactile sensors reflects a behavioral and movement-preparation state of the mouse.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.