Evidence map›Paper›PMID 31666315›Full record

ArticlemSphere2019

Dectin-2-Targeted Antifungal Liposomes Exhibit Enhanced Efficacy.

Suresh Ambati, Emma C Ellis, Jianfeng Lin, Xiaorong Lin, Zachary A Lewis, Richard B Meagher

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Pathogenesis and Triazole Resistance inInfection and drug resistance · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Altering the ligand specificity of DectiSomes.The Journal of biological chemistry · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Dendritic Cells: Multifunctional Roles in Host Defenses toJournal of fungi (Basel, Switzerland) · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Suresh AmbatiDepartment of Genetics, University of Georgia, Athens, Georgia, USA.
Emma C EllisDepartment of Genetics, University of Georgia, Athens, Georgia, USA.
Jianfeng LinDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.
Xiaorong LinDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-3390-8387
Zachary A LewisDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.
Richard B MeagherDepartment of Genetics, University of Georgia, Athens, Georgia, USA meagher@uga.edu.
University of Georgia · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Defining the genetic network governing cryptococcal morphological transitionR01AI140719 · NIAID · UNIVERSITY OF GEORGIA · PI Xiaorong Lin · 2018 to 2026
$4.1M
Targeted Pan-Antifungal LiposomesR01AI162989 · NIAID · UNIVERSITY OF GEORGIA · PI Zachary Lewis, Richard Brian Meagher · 2022 to 2026
$2.6M
Transcriptional repression by Polycomb Repressive Complex 2R01GM132644 · NIGMS · UNIVERSITY OF GEORGIA · PI LEWIS, ZACHARY · 2019 to 2022
$1.6M
Antifungal Liposomes Targeted to Cell Wall MannansR21AI148890 · NIAID · UNIVERSITY OF GEORGIA · PI MEAGHER, RICHARD BRIAN · 2020 to 2021
$415k
Antifungal ImunoliposomesR21AI144498 · NIAID · UNIVERSITY OF GEORGIA · PI MEAGHER, RICHARD BRIAN · 2019 to 2020
$415k
NCATS NIH HHS UL1 TR002378NIAID NIH HHS R01 AI140719NIAID NIH HHS R01 AI162989NIAID NIH HHS R21 AI144498NIAID NIH HHS R21 AI148890NIGMS NIH HHS R01 GM132644
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amphotericin BAntifungal AgentsAspergillus fumigatusCandida albicansCryptococcus neoformansFungiHEK293 CellsHT29 CellsHumansLectins, C-TypeLiposomesMycosesProtein BindingAmphotericin BAntifungal Agentsdectin-2, mouseLectins, C-TypeLiposomesamphotericin BDectin-2exopolysaccharide matrixinvasive fungal diseaseliposomesmannan

Identifiers

PMID31666315
PMCPMC6821932
OpenAlexW2982560523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.