SynthesisBMC psychiatry2019
Prevalence of perinatal depression among HIV-positive women: a systematic review and meta-analysis.
Synthesis in BMC psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Prevalence of Perinatal Anxiety and Related Disorders in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Trajectories of perinatal depression among women living with HIV in Uganda.Journal of global health · 2024Trial
- An Intervention to Improve Mental Health and HIV Care Engagement Among Perinatal Women in Malawi: A Pilot Randomized Controlled Trial.AIDS and behavior · 2023Trial
- Prevalence of neurotoxicity symptoms among postpartum women on isoniazid preventive therapy and efavirenz-based treatment for HIV: an exploratory objective of the IMPAACT P1078 randomized trial.BMC pregnancy and childbirth · 2023Trial
- A peer-facilitated psychological group intervention for perinatal women living with HIV and depression in Tanzania-Healthy Options: A cluster-randomized controlled trial.PLoS medicine · 2022Trial
- The Mental Health of Adults Living with HIV in Sub-Saharan Africa: Interventions along the HIV Care Continuum - A Systematic Review.AIDS and behavior · 2026Review
- An assessment of anxiety and depression among HIV-positive pregnant women in a tertiary hospital located in southeast Nigeria: a cross-sectional comparative analysis.Frontiers in psychiatry · 2026Article
- "When a man is stressed, it replicates in the house": Kenyan women's perspectives on the influence of male partners on perinatal mental health among women affected by HIV.PLOS global public health · 2026Article
- Clinical and socio-demographic characteristics associated with perinatal depression and human immunodeficiency virus.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026Article
- Mapping Psychosocial Interventions for Mental Health and Well-Being Among Pregnant Women Living with HIV: A Scoping Review.Journal of multidisciplinary healthcare · 2026Review
- Perinatal depression among women in pregnancy and postpartum periods in Gaborone, Botswana.BMC pregnancy and childbirth · 2025Article
- Diagnosis of postpartum depression and associated factors in South Africa: a cohort study of 47,697 women.Epidemiology and psychiatric sciences · 2025Article
- Depressive symptoms among women of reproductive age with and without HIV in the Southern United States.AIDS (London, England) · 2025Observational
- Psychosocial experiences of pregnant and postpartum women living with HIV in Ibadan, Oyo State.BMC public health · 2025Article
- HIV and Pregnancy: Navigating Complex Decision Making and Preventing Perinatal Transmission.Current HIV/AIDS reports · 2025Review
- Depression and associated factors among human immunodeficiency virus-positive pregnant women in sub-Saharan Africa: systematic review and meta-analysis.AJOG global reports · 2025Review
- Exploring the Intersection of Mental and Reproductive Health Among Women Living with HIV in Spain: A Qualitative Secondary Data Analysis.Healthcare (Basel, Switzerland) · 2025Article
- A pilot study to evaluate the feasibility and acceptability of a mobile phone counselling intervention for perinatal women living with HIV and depression in India.Oxford open digital health · 2025Article
- Clinical and psychosocial context of HIV perinatally infected young mothers in Harare, Zimbabwe: A longitudinal mixed-methods study.PloS one · 2025Article
- Engaging Family Members to Support Exclusive Breastfeeding, Responsive care, and Antiretroviral Therapy Adherence Among Families with Children who are HIV-Exposed and Uninfected.AIDS and behavior · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreasing attention has been paid to differences in the prevalence of perinatal depression by HIV status, although inconsistent results have been reported. The aim of this systematic review and meta-analysis was to assess the relationship between perinatal depression and HIV infection. A comprehensive meta-analysis of comparative studies comparing the prevalence of antenatal or postnatal depression between HIV-infected women and HIV-negative controls was conducted.
methodsStudies were identified through PubMed/Medline, Scopus, Web of Science, Cochrane Library, Embase and PsycINFO, and the reading of complementary references in August 2019. Subgroup analyses were performed for anticipated explanation of heterogeneity using methodological quality and pre-defined study characteristics, including study design, geographical location and depression screening tools for depression. The overall odds ratio (OR) and mean prevalence of each group were calculated.
resultsTwenty-three studies (from 21 publications), thirteen regarding antenatal depression and ten regarding postnatal depression were included, comprising 3165 subjects with HIV infection and 6518 controls. The mean prevalence of antenatal depressive symptoms in thirteen included studies was 36% (95% CI: 27, 45%) in the HIV-positive group and 26% (95% CI: 20, 32%) in the control group. The mean prevalence of postnatal depressive symptoms in ten included studies was 21% (95% CI: 14, 27%) in the HIV-positive group and 16% (95% CI: 10, 22%) in the control group. Women living with HIV have higher odds of antenatal (OR: 1.42; 95% CI: 1.12, 1.80) and postnatal depressive symptoms (OR: 1.58; 95% CI: 1.08, 2.32) compared with controls. Publication bias and moderate heterogeneity existed in the overall meta-analysis, and heterogeneity was partly explained by the subgroup analyses.
conclusionsWomen with HIV infection exhibit a significantly higher OR of antenatal and postnatal depressive symptoms compared with controls. For the health of both mother and child, clinicians should be aware of the significance of depression screening before and after delivery in this particular population and take effective measures to address depression among these women.
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