ArticleFEBS open bio2019
Effects of high-fat diet-induced adipokines and cytokines on colorectal cancer development.
Article in FEBS open bio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Efficacy and Safety of Habitual Consumption of a Food Supplement Containing Miraculin in Malnourished Cancer Patients: The CLINMIR Pilot Study.Nutrients · 2024Trial
- The role of serum adipokines in predicting response to neoadjuvant therapy in patients with locally advanced rectal cancer.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Characterization of nitroreductase gene A ofOpen life sciences · 2026Article
- Association between high fat diet and kidney stones based on the National Health and Nutrition Examination Survey (NHANES) 2007-2020: a cross-sectional study.Translational andrology and urology · 2025Article
- Assessment of the correlation between visceral adiposity and liver fat in metastatic colorectal cancer patients.International journal of colorectal disease · 2025Article
- CRLS1 influences liver metastasis in colon cancer by regulating lipid metabolism pathways.Functional & integrative genomics · 2025Article
- Plant-based dietary patterns, genetic risk, proteome, and lung cancer risk: a large prospective cohort study.European journal of nutrition · 2025Article
- The Potential Chemopreventive Effect ofInternational journal of molecular sciences · 2023Article
- Inhibition of NLRP3 by Fermented Quercetin Decreases Resistin-Induced Chemoresistance to 5-Fluorouracil in Human Colorectal Cancer Cells.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Adherence to the Danish food-based dietary guidelines and risk of colorectal cancer: a cohort study.British journal of cancer · 2021Article
- Growth Factors, PI3K/AKT/mTOR and MAPK Signaling Pathways in Colorectal Cancer Pathogenesis: Where Are We Now?International journal of molecular sciences · 2021Review
- High fat diet, gut microbiome and gastrointestinal cancer.Theranostics · 2021Review
- Expression of Genes Related to Lipid Handling and the Obesity Paradox in Melanoma: Database Analysis.JMIR cancer · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC) is the third most common tumor worldwide, and recent epidemiological studies have indicated that obesity contributes to the morbidity and mortality of CRC. Furthermore, obesity-related adipokines have been shown to be closely related to the incidence of CRC, but the underlying mechanisms are unclear. Here, we investigated the effects of high-fat diet-induced adipokines and cytokines on the development of CRC in vitro and in vivo. For the in vivo assays, we divided 2-week-old C57BL/6J-ApcMin/J male mice into three groups: normal-fat diet (ND), high-fat and high-sugar feed (HFHS), and high-fat and low-sugar feed (HFLS). After 1 week, all mice were injected with 20 mg·kg
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.