Evidence map›Paper›PMID 31665826›Full record

ArticleInternational wound journal2020

In vitro human cord blood platelet lysate characterisation with potential application in wound healing.

Paola Losi, Maria C Barsotti, Ilenia Foffa, Marianna Buscemi, Carolina V De Almeida, Marco Fabbri, Sabrina Gabbriellini, Francesca Nocchi, Silvia Ursino, Patrizia Urciuoli and 2 more

Abstract read
In one paragraph

Article in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management.Obstetrics and gynecology international · 2024
    Article
  5. Article
  6. Article
  7. Platelet Derivatives and the Immunomodulation of Wound Healing.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Paola LosiLaboratorio di Medicina Rigenerativa, Biomateriali e terapie avanzate, Institute of Clinical Physiology, National Research Council, Massa, Italy.ORCID https://orcid.org/0000-0002-1350-8626
Maria C BarsottiLaboratorio di Medicina Rigenerativa, Biomateriali e terapie avanzate, Institute of Clinical Physiology, National Research Council, Massa, Italy.
Ilenia FoffaLaboratorio di Medicina Rigenerativa, Biomateriali e terapie avanzate, Institute of Clinical Physiology, National Research Council, Massa, Italy.
Marianna BuscemiLaboratorio di Medicina Rigenerativa, Biomateriali e terapie avanzate, Institute of Clinical Physiology, National Research Council, Massa, Italy.
Carolina V De AlmeidaLaboratorio di Medicina Rigenerativa, Biomateriali e terapie avanzate, Institute of Clinical Physiology, National Research Council, Massa, Italy.
Marco FabbriLaboratorio di Immunogenetica, Medicina Trasfusionale e Biologia dei Trapianti, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Sabrina GabbrielliniLaboratorio di Immunogenetica, Medicina Trasfusionale e Biologia dei Trapianti, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Francesca NocchiLaboratorio di Immunogenetica, Medicina Trasfusionale e Biologia dei Trapianti, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Silvia UrsinoLaboratorio di Immunogenetica, Medicina Trasfusionale e Biologia dei Trapianti, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Patrizia UrciuoliLaboratorio di Immunogenetica, Medicina Trasfusionale e Biologia dei Trapianti, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Alessandro MazzoniMedicina Trasfusionale e Biologia dei Trapianti, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Giorgio SoldaniLaboratorio di Medicina Rigenerativa, Biomateriali e terapie avanzate, Institute of Clinical Physiology, National Research Council, Massa, Italy.

Funding

Fondazione Pisa "Prognostic evaluation of the use of three-dimen
6 · The paper itself

Abstract

Platelets contain abundant growth factors and cytokines that have a positive influence on the migration and proliferation of different cell types by modulating its physiopathological processes. As it is known that human umbilical cord blood platelet lysate (UCB-PL) contains a supraphysiological concentration of growth factors, in the present study, we investigated its effectiveness in wound-healing processes. Human UCB-PL was obtained by the freeze/thaw of platelet concentrate (1.1 × 10

Indexed as

Blood PlateletsCell ProliferationCells, CulturedCytokinesEndothelial Growth FactorsHumansHuman Umbilical Vein Endothelial CellsPlatelet-Rich PlasmaWound HealingWounds and InjuriesCytokinesEndothelial Growth Factorshuman umbilical cord bloodin vitro characterisationplatelet lysatewound healing

Identifiers

PMID31665826
PMCPMC7948753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.