Evidence map›Paper›PMID 31664967›Full record

ArticleBMC public health2019

Mental health disorders and alcohol use are associated with increased likelihood of smoking relapse among people living with HIV attending routine clinical care.

Cosmas M Zyambo, Greer A Burkholder, Karen L Cropsey, James H Willig, Craig M Wilson, C Ann Gakumo, Andrew O Westfall, Peter S Hendricks

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Interventions for tobacco use cessation in people living with HIV.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Differences in Cognition and Smoking Abstinence Rates Among People With and Without HIV Who Smoke.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. National Estimates of Prevalence, Time-Trend, and Correlates of Smoking in US People Living with HIV (NHANES 1999-2016).Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Article
  10. Tobacco Smoking and Associated Factors Among People Living With HIV in Uganda.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cosmas M ZyamboDepartment of Health Behavior, School of Public Health, University of Alabama at Birmingham, Birmingham, USA. czyambo256@gmail.com.
Greer A BurkholderDivision of Infectious Diseases, School of Medicine, University of Alabama at Birmingham, Birmingham, USA. gburkholder@uabmc.edu.
Karen L CropseyDepartment of Psychiatry, School of Medicine, University of Alabama at Birmingham, Birmingham, USA.
James H WilligDivision of Infectious Diseases, School of Medicine, University of Alabama at Birmingham, Birmingham, USA.
Craig M WilsonDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, USA.
C Ann GakumoDepartment of Nursing, University of Massachusetts, Boston, MA, USA.
Andrew O WestfallDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, USA.
Peter S HendricksDepartment of Health Behavior, School of Public Health, University of Alabama at Birmingham, Birmingham, USA.
University of Alabama at Birmingham · USUniversity of Massachusetts Boston · US

Funding

Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul A. Goepfert · 1988 to 2026
$84.1M
Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
FIC NIH HHS D43 TW010540NIAID NIH HHS P30 AI027767NIAID NIH HHS R24 AI067039
6 · The paper itself

Abstract

backgroundPeople living with HIV (PLWH) have a high level of interest in quitting smoking, but only a small proportion have sustainable abstinence 6 months after cessation. Few investigations have focused on relapse to smoking among PLWH. In this investigation, we evaluated the prevalence of relapse after smoking cessation and the characteristics associated with smoking relapse using a retrospective, longitudinal cohort of PLWH during an eight-year observation.

methodsAll patients aged ≥19 years that reported current smoking during the study period and then reported not smoking on a subsequent tobacco use questionnaire (quitters) were eligible for the study. In addition, patients required at least one subsequent follow-up visit after quitting where smoking status was again reported to allow for assessment of relapse. A Cox proportional hazard model was fit to evaluate factors associated with smoking relapse in PLWH attending routine clinical care.

resultsOf the 473 patients who quit smoking in the study, 51% relapsed. In multivariable analysis, factors significantly associated with a higher likelihood of relapse were anxiety symptoms (HR = 1.55, 95% CI [1.11, 2.17]) and at-risk alcohol use (HR = 1.74, 95% CI [1.06, 2.85]), whereas antiretroviral therapy (ART) adherence (HR = 0.65, 95% CI [0.49, 0.99]) and longer time in care (HR = 0.94, 95% CI [0.91, 0.98]) were associated with a reduced likelihood of relapse after cessation.

conclusionOur study underscores the high prevalence of smoking relapse that exists among PLWH after they quit smoking. Successful engagement in mental health care may enhance efforts to reduce relapse in the underserved populations of PLWH.

Indexed as

AdultAlabamaAlcohol DrinkingFemaleHIV InfectionsHumansMaleMental DisordersMiddle AgedPrevalenceRecurrenceRetrospective StudiesRisk FactorsSmokingSmoking CessationAlcohol useAnxietyDepressionHIVMental health disordersPLWHRelapseSmoking cessation

Identifiers

PMID31664967
PMCPMC6819600
OpenAlexW2982589508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.