Evidence map›Paper›PMID 31664927›Full record

ArticleBMC infectious diseases2019

Vibrio cholerae non-O1 - the first reported case of keratitis in a healthy patient.

Wei-Dar Chen, Li-Ju Lai, Wei-Hsiu Hsu, Tsung-Yu Huang

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Non-O1, Non-O139Tropical medicine and infectious disease · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Rational Use of Antibiotics and Education ImprovedAntibiotics (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wei-Dar ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Li-Ju LaiDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Wei-Hsiu HsuDepartment of Chinese Medicine, School of Medicine, Chang Gung University, Taoyuan, Taiwan.
Tsung-Yu HuangDivision of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan. r12045@cgmh.org.tw.ORCID http://orcid.org/0000-0003-1998-5631
Chang Gung University · TWChiayi Chang Gung Memorial Hospital · TW

Funding

Chang Gung Medical Foundation CORPG6E0051 & CMRPG6D0362
6 · The paper itself

Abstract

backgroundVibrio cholerae non-O1 is a virulent pathogen that causes significant morbidity and mortality in humans. Herein, we report a case of corneal ulcer caused by this pathogen. CASE PRESENTATION: A 59-year-old fisherman with no systemic history was struck in the right eye by a marine shrimp and developed keratitis. Corneal scrapping culture revealed the presence of the V. cholerae non-O1, and its identification was confirmed by Analytical Profile Index 20E system and polymerase chain reaction. He was successfully treated with topical levofloxacin (0.3%) and fortified amikacin (12.5 mg/mL) for 2 weeks. The visual acuity recovered to 20/25 after treatment without complications.

conclusionsThis is the first case report of keratitis caused by V. cholerae non-O1 strain. Ocular injury by marine creatures and contaminated seawater can contribute to severe corneal ulcer. Early diagnosis can be achieved by meticulous history taking and a comprehensive laboratory workup. Simultaneously, an effective antibiotic therapy can lead to a positive outcome.

Indexed as

Administration, TopicalAmikacinAnti-Bacterial AgentsAquatic OrganismsCorneal UlcerEyeHumansKeratitisLevofloxacinMaleMiddle AgedPolymerase Chain ReactionSeawaterTreatment OutcomeVibrio cholerae non-O1Vibrio InfectionsAmikacinAnti-Bacterial AgentsLevofloxacinCorneal ulcerKeratitisMarine shrimpVibrio cholerae non-O1Virulence factor

Identifiers

PMID31664927
PMCPMC6820971
OpenAlexW2982658375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.