Evidence map›Paper›PMID 31664889›Full record

ArticleStress (Amsterdam, Netherlands)2020

Data-driven discovery of mid-pregnancy immune markers associated with maternal lifetime stress: results from an urban pre-birth cohort.

Whitney Cowell, Elena Colicino, Alison G Lee, Michelle Bosquet Enlow, Julie D Flom, Cecilia Berin, Robert O Wright, Rosalind J Wright

Open access · greenAbstract read
In one paragraph

Article in Stress (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. The Exposome Approach to Decipher the Role of Multiple Environmental and Lifestyle Determinants in Asthma.International journal of environmental research and public health · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Whitney CowellDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Elena ColicinoDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alison G LeeDivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Michelle Bosquet EnlowBoston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Julie D FlomDepartment of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Cecilia BerinDepartment of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Robert O WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Rosalind J WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Icahn School of Medicine at Mount Sinai · USHarvard University · US

Funding

Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Maria Jose Rosa · 2014 to 2026
$21.3M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUG3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CARROLL, KECIA NICOLE, WRIGHT, ROBERT O · 2016 to 2024
$20.6M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
Maternal Traumatic Stress, Oxidative Stress, Antioxidant Exposures, and Child Asthma and Lung FunctionR01HL132338 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CARROLL, KECIA NICOLE, WRIGHT, ROSALIND J · 2017 to 2021
$3.8M
Perinatal Programming of Infant Stress Reactivity and the Atopic PhenotypeR01HL095606 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOSQUET ENLOW, MICHELLE A, WRIGHT, ROSALIND J · 2010 to 2013
$3.1M
Prenatal stress and epigenetic programming of the HPA axis and autonomic balanceR01HL114396 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2012 to 2015
$2.8M
Prenatal PM2.5 and programming of respiratory outcomes: Placental biomarkers and effect modification by stressK23HL135349 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LEE, ALISON G · 2017 to 2021
$884k
NHLBI NIH HHS K23 HL135349NHLBI NIH HHS R01 HL095606NHLBI NIH HHS R01 HL114396NHLBI NIH HHS R01 HL132338NICHD NIH HHS T32 HD049311NIEHS NIH HHS P30 ES023515NIH HHS UG3 OD023337NIH HHS UH3 OD023337
6 · The paper itself

Abstract

Changes to the maternal inflammatory milieu may be a mechanism through which maternal psychosocial stress is transmitted to the fetus. Research investigating a limited number of immune markers may miss important signals. We take a proteomics approach to investigate maternal lifetime stress and 92 biomarkers of immune system status. Participants were enrolled in an urban, dual-site (Boston,

Indexed as

MothersStress, PsychologicalBiomarkersCohort StudiesFemaleFetal DevelopmentFibroblast Growth Factor-23HumansPregnancyBiomarkersFGF23 protein, humanFibroblast Growth Factor-23CX3CL1fractalkineImmunepregnancystresstrauma

Identifiers

PMID31664889
PMCPMC7210067
OpenAlexW2982474176

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.