Evidence map›Paper›PMID 31664756›Full record

ArticleDermatologic therapy2019

Real-life treatment of cutaneous warts with cantharidin podophyllin salicylic acid solution.

Anh Ly Nguyen, Koen D Quint, Jan Nico Bouwes Bavinck, Angelina Erceg, Wim J A de Kort, John E M Körver

Open access · hybridAbstract read
In one paragraph

Article in Dermatologic therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anh Ly NguyenDepartment of Dermatology, Amphia Hospital, Breda, The Netherlands.ORCID 0000-0003-1050-0634
Koen D QuintDepartment of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
Jan Nico Bouwes BavinckDepartment of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
Angelina ErcegDepartment of Dermatology, Amphia Hospital, Breda, The Netherlands.
Wim J A de KortDepartment of Dermatology, Amphia Hospital, Breda, The Netherlands.
John E M KörverDepartment of Dermatology, Amphia Hospital, Breda, The Netherlands.
Amphia Ziekenhuis · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients often request treatment of their burdensome cutaneous warts. However, a safe and effective treatment for cutaneous warts is lacking. This study evaluates treatment outcome, side effects, and patient satisfaction after topical application of cantharidin 1% podophyllin 2% salicylic acid 30% (CPS1) solution in a large series of children and adults with cutaneous warts. Fifty-two children and 83 adults with warts, treated with CPS1 solution between October 2012 and October 2014, were included. Complete clearance of warts occurred in 86.5% of children and 62.7% of adults treated with CPS1 solution (p < .01). Resolution of warts was partial in 3.9 and 24.1% and absent in 9.6 and 13.2% of children and adults respectively. Side effects were present in 41.2% of children and 46.3% of adults (p = .7). Most common side effects were blistering, pain, and burning sensation. No serious adverse events occurred. On a 10-point scale, median patient satisfaction score was 9.0 (interquartile range 7.8-10.0) and 8.0 (interquartile range 5.1-9.7) for children and adults respectively (p < .01). CPS1 solution is a safe and promising treatment modality with a high clearance and high patient satisfaction rate for the management of cutaneous warts, particularly in children.

Indexed as

Administration, CutaneousAdultAge FactorsCantharidinChildCohort StudiesFemaleHumansKeratolytic AgentsMalePatient SatisfactionPodophyllinRetrospective StudiesSalicylic AcidTreatment OutcomeWartsCantharidinKeratolytic AgentsPodophyllinSalicylic Acidcantharidin podophyllin salicylic acid solutionclearance ratepatient satisfactiontreatment outcomewarts

Identifiers

PMID31664756
PMCPMC6916542
OpenAlexW2982590758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.