ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
Brain abnormalities in myelomeningocele patients.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Prevalence of epilepsy and structural brain anomalies in spina bifida aperta.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Long-term cognitive outcomes of Chiari II malformation and corpus callosum abnormalities in myelomeningocele.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Review
- Differences in brain development and need for CSF diversion based on MMC level: Comparison between prenatal and postnatal repair.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- A qualitative analysis of patient and caregiver experiences with myelomeningocele through online discussion boards.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Long-Term Imaging Follow-up from the Management of Myelomeningocele Study.AJNR. American journal of neuroradiology · 2023Article
- Atlantoaxial limited dorsal myeloschisis: A report of two cases and review of literature.Brain & spine · 2021Article
- Intrauterine cytomegalovirus infection: a possible risk for cerebral palsy and related to its clinical features, neuroimaging findings: a retrospective study.BMC pediatrics · 2020Article
- Severe myelomeningocele in the fourth pregnancy of a 29-year-old woman: a case report.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
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8 authors.
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Abstract
backgroundMyelomeningocele (MMC) is often related to hydrocephalus and Chiari malformation (CM) type 2; however, other brain abnormalities have been reported in this population. In order to better understand and quantify other forebrain abnormalities, we analyzed magnetic resonance imaging (MRI) of MMC patients treated in utero or postnatal.
methodsBetween January 2014 and March 2017, 59 MMC were treated in our hospital. Thirty-seven patients (32 postnatal and 5 intrautero repair) had brain MRI and were enrolled at the study. MRI was analyzed by two experienced neuroradiologists to identify the supra and infratentorial brain abnormalities.
resultsA wide range of brain abnormalities was consistently identified in MMC patients. As expected, the most common were hydrocephalus (94.5%) and CM type II (89.1%). Of note, we found high incidence of corpus callosum abnormalities (86.4%), mostly represented by dysplasia (46%).
conclusionsThe data are consistent with the concept that brain abnormalities related to MMC can be both infratentorial and supratentorial, cortical, and subcortical. More studies are needed to correlate these forebrain abnormalities to long-term functional outcome and their prognostic value for these patients.
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