ArticleThe ISME journal2020
Novel probiotic approach to counter Paenibacillus larvae infection in honey bees.
Article in The ISME journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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Who cites it
90 citing papers in PubMed, 151 citations in OpenAlex.
- Probiotic Characterization of Honey Bee-Associated Lactic Acid Bacteria and Their Impact on Colony Growth.Probiotics and antimicrobial proteins · 2026Article
- Comparative genomics and phenotypic divergence of ERIC I and ERIC II genotypes of Paenibacillus larvae, the causative agent of American Foulbrood disease.PLoS pathogens · 2026Article
- Symbiont-Mediated Detoxification of Xenobiotics in Honey Bees.Microbial biotechnology · 2026Review
- Bacterial supplementation shapes honey bee gut microbiota and host metabolism under controlled and field conditions.mSystems · 2026Article
- In Vivo and In Vitro Evaluation of Probiotic and Postbiotic Strategies Against Foulbrood in Honeybees.Probiotics and antimicrobial proteins · 2026Article
- How Environmental and Ecological Stressors Reprogram Honey Bee Chemistry Through the Microbiome-Metabolome Axis.Insects · 2026Review
- Review
- Probiotic Assessment of Lactic Acid Bacteria Strains and Consortia for Enhancing Honey Bee Health and Nutrition.Microorganisms · 2026Article
- Non-thermal atmospheric pressure plasma inactivation of Paenibacillus larvae, the causative agent of American foulbrood in honeybees (Apis mellifera).Scientific reports · 2026Article
- Melatonin as a Potential Dietary Supplement to Counteract Glyphosate-Induced Decline in Honeybee Populations.Insects · 2026Article
- Deformed Wing Virus infection induces immunosuppression and gut dysbiosis in honey bees.Animal microbiome · 2026Article
- How "pro" are probiotics for wildlife species? Novel data, lack of evidence, and future directions.ISME communications · 2026Article
- Article
- Hive-associated bacteria improve honeybee survival duringbioRxiv : the preprint server for biology · 2025Article
- Gut microbiota profiling of Apis cerana indica across biodiversity hotspots in the Western Ghats, India.Molecular biology reports · 2025Article
- Evaluation of Combined Use of Protein and Postbiotics Feed Supplements in Honey Beehives in Autumn and Spring.Probiotics and antimicrobial proteins · 2025Article
- Parasitic Mites of Honey Bees (Apis Spp.): A Detailed Review of Varroa destructor in Parasitism, Pathogen Transmission and its Management.Acta parasitologica · 2025Review
- Lactic Acid Bacteria: A Probiotic to Mitigate Pesticide Stress in Honey Bee.Probiotics and antimicrobial proteins · 2025Review
- Probiotic effects on ectoparasitic mite infestations in honey bees (Microbiology spectrum · 2025Article
- Testing the Effectiveness of a Commercially Sold Probiotic on Restoring the Gut Microbiota of Honey Bees: a Field Study.Probiotics and antimicrobial proteins · 2025Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
American foulbrood (AFB) is a highly virulent disease afflicting honey bees (Apis mellifera). The causative organism, Paenibacillus larvae, attacks honey bee brood and renders entire hives dysfunctional during active disease states, but more commonly resides in hives asymptomatically as inactive spores that elude even vigilant beekeepers. The mechanism of this pathogenic transition is not fully understood, and no cure exists for AFB. Here, we evaluated how hive supplementation with probiotic lactobacilli (delivered through a nutrient patty; BioPatty) affected colony resistance towards a naturally occurring AFB outbreak. Results demonstrated a significantly lower pathogen load and proteolytic activity of honey bee larvae from BioPatty-treated hives. Interestingly, a distinctive shift in the microbiota composition of adult nurse bees occurred irrespective of treatment group during the monitoring period, but only vehicle-supplemented nurse bees exhibited higher P. larvae loads. In vitro experiments utilizing laboratory-reared honey bee larvae showed Lactobacillus plantarum Lp39, Lactobacillus rhamnosus GR-1, and Lactobacillus kunkeei BR-1 (contained in the BioPatty) could reduce pathogen load, upregulate expression of key immune genes, and improve survival during P. larvae infection. These findings suggest the usage of a lactobacilli-containing hive supplement, which is practical and affordable for beekeepers, may be effective for reducing enzootic pathogen-related hive losses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.