Evidence map›Paper›PMID 31664141›Full record

Trial reportScientific reports2019

Pre-pregnancy underweight and obesity are positively associated with small-for-gestational-age infants in a Chinese population.

Yuan Hua Chen, Li Li, Wei Chen, Zhi Bing Liu, Li Ma, Xing Xing Gao, Jia Liu He, Hua Wang, Mei Zhao, Yuan Yuan Yang and 1 more

Abstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  17. Markers of inflammation in obese pregnant women: Adenosine deaminase and high sensitive C - reactive protein.European journal of obstetrics & gynecology and reproductive biology: X · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuan Hua ChenSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China. yuanhuach@126.com.
Li LiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
Wei ChenSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China.
Zhi Bing LiuSchool of Public Health, Anhui Medical University, Hefei, 230032, China.
Li MaSchool of Public Health, Anhui Medical University, Hefei, 230032, China.
Xing Xing GaoSchool of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China.
Jia Liu HeSchool of Public Health, Anhui Medical University, Hefei, 230032, China.
Hua WangSchool of Public Health, Anhui Medical University, Hefei, 230032, China.ORCID http://orcid.org/0000-0002-0093-9275
Mei ZhaoSchool of Nursing, Anhui Medical University, Hefei, 230032, China.
Yuan Yuan YangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
De Xiang XuSchool of Public Health, Anhui Medical University, Hefei, 230032, China. xudex@126.com.ORCID http://orcid.org/0000-0002-5126-4335

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between suboptimal pre-pregnancy body mass index (BMI) and small-for-gestational-age (SGA) infants is not well defined. We investigated the association between pre-pregnancy BMI and the risk of SGA infants in a Chinese population. We performed a cohort study among 12029 mothers with a pregnancy. This cohort consisted of pregnant women that were: normal-weight (62.02%), underweight (17.09%), overweight (17.77%) and obese (3.12%). Birth sizes were reduced in the underweight and obese groups compared with the normal-weight group. Linear regression analysis indicated that birth size was positively associated with BMI in both the underweight and normal-weight groups. Further analysis showed that 12.74% of neonates were SGA infants in the underweight group, higher than 7.43% of neonates reported in the normal-weight group (adjusted RR = 1.92; 95% CI: 1.61, 2.30). Unexpectedly, 17.60% of neonates were SGA infants in the obese group, much higher than the normal-weight group (adjusted RR = 2.17; 95% CI: 1.57, 3.00). Additionally, 18.40% of neonates were large-for-gestational-age (LGA) infants in the obese group, higher than 7.26% of neonates reported in the normal-weight group (adjusted RR = 3.00; 95% CI: 2.21, 4.06). These results suggest that pre-pregnancy underweight increases the risk of SGA infants, whereas obesity increases the risks of not only LGA infants, but also SGA infants.

Indexed as

Infant, Small for Gestational AgeAdultChinaFemaleHumansInfant, NewbornPregnancyPregnancy in ObesityRisk FactorsThinness

Identifiers

PMID31664141
PMCPMC6820714

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.