Evidence map›Paper›PMID 31664132›Full record

ArticleScientific reports2019

Functional connectivity of music-induced analgesia in fibromyalgia.

Victor Pando-Naude, Fernando A Barrios, Sarael Alcauter, Erick H Pasaye, Lene Vase, Elvira Brattico, Peter Vuust, Eduardo A Garza-Villarreal

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Music-based interventions for chronic pain management.The Cochrane database of systematic reviews · 2026
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  4. Article
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  8. Review
  9. Fibromyalgia: A Multifactorial Pain Disorder.International journal of molecular sciences · 2026
    Review
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Victor Pando-NaudeSubdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría "Ramón de la Fuente Muñiz", México City, México.
Fernando A BarriosDepartment of Behavioral and Cognitive Neurobiology, Brain Mapping Lab, Institute of Neurobiology, Universidad Nacional Autónoma de México campus Juriquilla, Querétaro, México.ORCID http://orcid.org/0000-0002-5699-4222
Sarael AlcauterDepartment of Behavioral and Cognitive Neurobiology, Brain Mapping Lab, Institute of Neurobiology, Universidad Nacional Autónoma de México campus Juriquilla, Querétaro, México.
Erick H PasayeMagnetic Resonance Unit, Institute of Neurobiology, Universidad Nacional Autónoma de México campus Juriquilla, Querétaro, México.
Lene VaseDepartment of Psychology and Behavioral Sciences, University of Aarhus, Aarhus, Denmark.
Elvira BratticoCenter for Music in the Brain, University of Aarhus, Aarhus, Denmark.
Peter VuustCenter for Music in the Brain, University of Aarhus, Aarhus, Denmark.
Eduardo A Garza-VillarrealSubdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría "Ramón de la Fuente Muñiz", México City, México. egarza@comunidad.unam.mx.ORCID http://orcid.org/0000-0003-1381-8648
Institute of Neurobiology · BGRoyal Academy of Music · DKAarhus University · DKAutonomous University of Queretaro · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Listening to self-chosen, pleasant and relaxing music reduces pain in fibromyalgia (FM), a chronic centralized pain condition. However, the neural correlates of this effect are fairly unknown. In our study, we wished to investigate the neural correlates of music-induced analgesia (MIA) in FM patients. To do this, we studied 20 FM patients and 20 matched healthy controls (HC) acquiring rs-fMRI with a 3T MRI scanner, and pain data before and after two 5-min auditory conditions: music and noise. We performed resting state functional connectivity (rs-FC) seed-based correlation analyses (SCA) using pain and analgesia-related ROIs to determine the effects before and after the music intervention in FM and HC, and its correlation with pain reports. We found significant differences in baseline rs-FC between FM and HC. Both groups showed changes in rs-FC after the music condition. FM patients reported MIA that was significantly correlated with rs-FC decrease between the angular gyrus, posterior cingulate cortex and precuneus, and rs-FC increase between amygdala and middle frontal gyrus. These areas are related to autobiographical and limbic processes, and auditory attention, suggesting MIA may arise as a consequence of top-down modulation, probably originated by distraction, relaxation, positive emotion, or a combination of these mechanisms.

Indexed as

AnalgesiaMusicAdultAgedBrain MappingCase-Control StudiesFemaleFibromyalgiaHumansMagnetic Resonance ImagingMaleMiddle AgedPain ManagementYoung Adult

Identifiers

PMID31664132
PMCPMC6820536
OpenAlexW2982415033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.