Evidence map›Paper›PMID 31664121›Full record

Trial reportScientific reports2019

Mode of delivery and pregnancy outcomes in preterm birth: a secondary analysis of the WHO Global and Multi-country Surveys.

Bao Yen Luong Thanh, Pisake Lumbiganon, Porjai Pattanittum, Malinee Laopaiboon, Joshua P Vogel, Olufemi T Oladapo, Cynthia Pileggi-Castro, Rintaro Mori, Kapila Jayaratne, Zahida Qureshi and 1 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Article
  9. A Compassion-Focused Approach to Support Parents After Preterm Birth.Clinical child and family psychology review · 2025
    Review
  10. Probiotic biogeography and sepsis prevention in the neonatal intestine.bioRxiv : the preprint server for biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bao Yen Luong ThanhDepartment of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, 123 Moo 16 Mittapap Rd., Nai-Muang, Muang District, Khon Kaen, 40002, Thailand.ORCID http://orcid.org/0000-0003-3511-6698
Pisake LumbiganonDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, 123 Moo 16 Mittapap Rd., Nai-Muang, Muang District, Khon Kaen, 40002, Thailand. pisake@kku.ac.th.
Porjai PattanittumDepartment of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, 123 Moo 16 Mittapap Rd., Nai-Muang, Muang District, Khon Kaen, 40002, Thailand.
Malinee LaopaiboonDepartment of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, 123 Moo 16 Mittapap Rd., Nai-Muang, Muang District, Khon Kaen, 40002, Thailand.
Joshua P VogelUNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research World Health Organization, Avenue Appia 20, Geneva, Switzerland.
Olufemi T OladapoUNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research World Health Organization, Avenue Appia 20, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-3371-5892
Cynthia Pileggi-CastroIndependent Consultant, Geneva, Switzerland.
Rintaro MoriDepartment of Health Policy, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Kapila JayaratneMaternal & Child Morbidity & Mortality Surveillance, Family Health Bureau - Ministry of Health, 231 De Saram Place, Colombo 10, Colombo, Sri Lanka.
Zahida QureshiDepartment of Obstetrics and Gynaecology, School of Medicine, College of Health Sciences, University of Nairobi, Nairobi, Kenya.
Joã SouzaUNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research World Health Organization, Avenue Appia 20, Geneva, Switzerland.

Funding

World Health Organization 001
6 · The paper itself

Abstract

Many studies have been conducted to examine whether Caesarean Section (CS) or vaginal birth (VB) was optimal for better maternal and neonatal outcomes in preterm births. However, findings remain unclear. Therefore, this secondary analysis of World Health Organization Global Survey (GS) and Multi-country Survey (MCS) databases was conducted to investigate outcomes of preterm birth by mode of delivery. Our sample were women with singleton neonates (15,471 of 237 facilities from 21 countries in GS; and 15,053 of 239 facilities from 21 countries in MCS) delivered between 22 and <37 weeks of gestation. We assessed association between mode of delivery and pregnancy outcomes in singleton preterm births by multilevel logistic regression adjusted for hierarchical data. The prevalences of women with preterm birth delivered by CS were 31.0% and 36.7% in GS and MCS, respectively. Compared with VB, CS was associated with significantly increased odds of maternal intensive care unit admission, maternal near miss, and neonatal intensive care unit admission but significantly decreased odds of fresh stillbirth, and perinatal death. However, since the information on justification for mode of delivery (MOD) were not available, our results of the potential benefits and harms of CS should be carefully considered when deciding MOD in preterm births.

Indexed as

Cesarean SectionPerinatal DeathPerinatal MortalityAdultCross-Sectional StudiesFemaleHumansInfant, NewbornPregnancyPremature BirthPrevalenceStillbirth

Identifiers

PMID31664121
PMCPMC6820722

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.