ArticleScientific reports2019
Neural control of fasting-induced torpor in mice.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 45 citations in OpenAlex.
- Clocks slide rather than freeze during torpor in the mouse.iScience · 2026Article
- Neural Control of Homeothermy, Torpor, and Hibernation.Annual review of neuroscience · 2026Review
- Neural circuits of torpor.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026Article
- Daily torpor in the Djungarian hamster (Phodopus sungorus) is orchestrated by the suprachiasmatic nucleus: evidence from immediate early gene mapping and nucleus-specific sequencing.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026Article
- Inhibition of daily torpor in mice requires calories, not just feeding: a potential role for GLP-1.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026Article
- Estrous cycle modulates fasting-induced torpor propensity via hypothalamic estrogen signalling.Scientific reports · 2026Article
- Spatial mapping of influenza and coronavirus receptors in the respiratory and intestinal tract epithelium of beef cattle using advanced PixF image analysis.Scientific reports · 2025Article
- Synthetic torpor: advancing metabolic regulation for medical innovations.Nature metabolism · 2025Review
- The cold truth: torpor as a confound in studies of caloric restriction.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025Review
- Perspectives: Comparison of deep learning segmentation models on biophysical and biomedical data.Biophysical journal · 2025Article
- A torpor-like state in mice slows blood epigenetic aging and prolongs healthspan.Nature aging · 2025Article
- Cold is hot for slowing aging.Nature aging · 2025Article
- The Art of Chilling Out: How Neurons Regulate Torpor.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- Brainstem BDNF neurons are downstream of GFRAL/GLP1R signalling.Nature communications · 2024Article
- A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan.bioRxiv : the preprint server for biology · 2024Article
- Fluorescent Neuronal Cells v2: multi-task, multi-format annotations for deep learning in microscopy.Scientific data · 2024Article
- Activation of oxytocinergic neurons enhances torpor in mice.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024Article
- Activation of orexin-A (hypocretin-1) receptors in the Raphe Pallidus at different ambient temperatures in the rat: effects on thermoregulation, cardiovascular control, sleep, and feeding behavior.Frontiers in neuroscience · 2024Article
- Hippocampal neuroimmune response in mice undergoing serial daily torpor induced by calorie restriction.Frontiers in neuroanatomy · 2024Article
- Hypothalamic control of torpor and hibernation.Temperature (Austin, Tex.) · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Torpor is a peculiar mammalian behaviour, characterized by the active reduction of metabolic rate, followed by a drop in body temperature. To enter torpor, the activation of all thermogenic organs that could potentially defend body temperature must be prevented. Most of these organs, such as the brown adipose tissue, are controlled by the key thermoregulatory region of the Raphe Pallidus (RPa). Currently, it is not known which brain areas mediate the entrance into torpor. To identify these areas, the expression of the early gene c-Fos at torpor onset was assessed in different brain regions in mice injected with a retrograde tracer (Cholera Toxin subunit b, CTb) into the RPa region. The results show a network of hypothalamic neurons that are specifically activated at torpor onset and a direct torpor-specific projection from the Dorsomedial Hypothalamus to the RPa that could putatively mediate the suppression of thermogenesis during torpor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.