ArticleScientific reports2019
Late-Onset Sepsis as a Risk Factor for Bronchopulmonary Dysplasia in Extremely Low Birth Weight Infants: A Nationwide Cohort Study.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Risk factors for bronchopulmonary dysplasia in preterm infants: a systematic review and meta-analysis.PeerJ · 2025Pooled it
- Does neonatal sepsis affect the lung function of children and adults born prematurely?Pediatric research · 2026Article
- Preterm Infant and Caregiver Outcomes After Maternal Appendectomy During Pregnancy.Healthcare (Basel, Switzerland) · 2026Article
- Association between multi-oil fat emulsion and bronchopulmonary dysplasia in preterm infants <32 weeks.Translational pediatrics · 2026Article
- Association between neonatal sepsis and lung function in school-age children born preterm.Pediatric research · 2026Article
- Culture-Confirmed Bacterial Sepsis and Invasive Fungal Infection in Preterm Infants: NICU Resource Burden, Major Morbidity, and Caregiver Psychological Distress.Diseases (Basel, Switzerland) · 2026Article
- Article
- NeoCLIP: a self-supervised foundation model for the interpretation of neonatal radiographs.NPJ digital medicine · 2025Article
- Machine learning-based risk prediction models for bronchopulmonary dysplasia in preterm infants: a high-altitude cohort study.BMJ paediatrics open · 2025Article
- Nutritional Management for Preterm Infants with Common Comorbidities: A Narrative Review.Nutrients · 2025Review
- Mother's own milk and bronchopulmonary dysplasia in appropriate for gestational age preterm infants.European journal of clinical nutrition · 2024Article
- Conditional knockout of ITGB4 in bronchial epithelial cells directs bronchopulmonary dysplasia.Journal of cellular and molecular medicine · 2023Article
- Microbial signatures in amniotic fluid at preterm birth and association with bronchopulmonary dysplasia.Respiratory research · 2023Observational
- Risk factors and machine learning prediction models for bronchopulmonary dysplasia severity in the Chinese population.World journal of pediatrics : WJP · 2023Article
- Longer duration of initial invasive mechanical ventilation is still a crucial risk factor for moderate-to-severe bronchopulmonary dysplasia in very preterm infants: a multicentrer prospective study.World journal of pediatrics : WJP · 2023Article
- Development and Validation of a Risk Scoring Tool for Bronchopulmonary Dysplasia in Preterm Infants Based on a Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Article
- Outcomes of and factors associated with the development of bronchopulmonary dysplasia with pulmonary hypertension in very low birth weight infants: A retrospective study in a medical center.Frontiers in pediatrics · 2023Article
- Article
- Healthcare-associated Infections in Very Low Birth-weight Infants in a South African Neonatal Unit: Disease Burden, Associated Factors and Short-term Outcomes.The Pediatric infectious disease journal · 2022Article
- Catheter-related bloodstream infections in infants hospitalized in neonatal intensive care units: a single center study.Scientific reports · 2022Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to determine the effect of late-onset sepsis (LOS) on the development of bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants. A prospective cohort study was performed using data collected from 64 centres registered in the Korean national registry. LOS was defined as a positive blood culture and antibiotics treatment after 72 hours of life and prior to 36 weeks postmenstrual age (PMA). Data on the causative organisms were collected and analysed for respiratory outcomes. Among the 1,434 ELBW infants who survived to 36 weeks PMA, 481 (34%) developed LOS caused by bacteria (n = 405), fungi (n = 28), or both (n = 48). The incidence of BPD was significantly associated with LOS in both the entire cohort and the propensity score-matched cohort. Two or more LOS episodes were a risk factor for BPD. The impact of multiple episodes of LOS on BPD was prominent in infants who received mechanical ventilation for two weeks or less. The estimated odds ratios for BPD and severe BPD were greater with fungal LOS than with bacterial LOS. In conclusion, LOS, particularly complicated by multiple episodes and/or fungi, was a risk factor for BPD in ELBW infants.
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