Evidence map›Paper›PMID 31664013›Full record

ArticleOptometry and vision science : official publication of the American Academy of Optometry2019

The Veterans Affairs Continuous Positive Airway Pressure Use and Diabetic Retinopathy Study.

James Patrick Smith, Luke G Cyr, Laura K Dowd, Kyla S Duchin, Priscilla A Lenihan, Jennifer Sprague

Open access · greenAbstract read
In one paragraph

Article in Optometry and vision science : official publication of the American Academy of Optometry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Adipose Tissue Hypoxia in Obesity: Clinical Reappraisal of Hypoxia Hypothesis.Advances in experimental medicine and biology · 2024
    Review
  4. Article
  5. Peripheral retinal neovascularization in a patient with obstructive sleep apnea.American journal of ophthalmology case reports · 2022
    Article
  6. Sleep and eye disease: A review.Clinical & experimental ophthalmology · 2022
    Review
  7. Article
  8. Obstructive sleep apnea and the retina: a review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Review
  9. Association of continuous positive airway pressure adherence with complications in patients with type 2 diabetes and obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  10. Ocular Complications of Obstructive Sleep Apnea.Journal of clinical medicine · 2021
    Review
  11. Hypoxia-inducible factors and diabetes.The Journal of clinical investigation · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

James Patrick Smith
Luke G CyrVA Maine Health Care System, Augusta, Maine.
Laura K DowdVA Maine Health Care System, Augusta, Maine.
Kyla S DuchinVA Maine Health Care System, Augusta, Maine.
Priscilla A LenihanVA Maine Health Care System, Augusta, Maine.
Jennifer SpragueVA Maine Health Care System, Augusta, Maine.
MaineHealth · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

significanceObstructive sleep apnea has been linked to the development and progression of diabetic retinopathy. In this study, diabetic patients compliant with continuous positive airway pressure therapy (CPAP) for sleep apnea were less likely to have retinopathy, emphasizing the benefits and potential therapeutic role of CPAP in individuals with both conditions. PURPOSE: The aim of this study was to compare the prevalence of diabetic retinopathy in type 2 diabetic patients with obstructive sleep apnea who were compliant with CPAP therapy with those who were not compliant with CPAP therapy.

methodsA retrospective cross-sectional review of type 2 diabetic patients using CPAP for obstructive sleep apnea was conducted. The prevalence of retinopathy was identified, and groups with and without retinopathy were compared using univariate analyses and multivariate logistic regression.

resultsThe prevalence of retinopathy was 19.6% (n = 321). Retinopathy was significantly less prevalent in those compliant with CPAP (odds ratio, 0.54; 95% confidence interval, 0.31 to 0.94; P = .04). The relationship remained statistically significant when adjusting for other factors known to impact the course of diabetic eye disease.

conclusionsIncreased CPAP compliance may mitigate the risk of developing diabetic retinopathy in type 2 diabetic patients with obstructive sleep apnea.

Indexed as

Continuous Positive Airway PressureRespiratory TherapyAdultCross-Sectional StudiesDiabetes Mellitus, Type 2Diabetic RetinopathyDisease ProgressionFemaleHumansLogistic ModelsMaleMiddle AgedPatient CompliancePrevalenceRetrospective StudiesSleep Apnea, Obstructive

Identifiers

PMID31664013
PMCPMC6855331
OpenAlexW2982384400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.