Evidence map›Paper›PMID 31663976›Full record

ArticleSexually transmitted diseases2019

Clinicians' Use of Intravaginal Boric Acid Maintenance Therapy for Recurrent Vulvovaginal Candidiasis and Bacterial Vaginosis.

Anna Powell, Khalil G Ghanem, Linda Rogers, Ashley Zinalabedini, Rebecca M Brotman, Jonathan Zenilman, Susan Tuddenham

Open access · greenAbstract read
In one paragraph

Article in Sexually transmitted diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Bacterial vaginosis.Nature reviews. Disease primers · 2025
    Review
  7. Review
  8. Vaginal Sheets withGels (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Effects of Boric Acid Gel on VaginalFrontiers in immunology · 2022
    Article
  14. Article
  15. Review
  16. Effects of 3% Boric Acid Solution on CutaneousFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna PowellFrom the Department of Obstetrics and Gynecology.
Khalil G GhanemDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine.
Linda RogersFrom the Department of Obstetrics and Gynecology.
Ashley ZinalabediniFrom the Department of Obstetrics and Gynecology.
Rebecca M BrotmanInstitute for Genome Sciences, University of Maryland, Baltimore, MD.
Jonathan ZenilmanDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine.
Susan TuddenhamDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine.
Johns Hopkins Medicine · USUniversity of Maryland, Baltimore · US

Funding

Dysbiosis, Recurrent Bacterial Vaginosis and the Vaginal MicrobiomeK23AI125715 · NIAID · JOHNS HOPKINS UNIVERSITY · PI TUDDENHAM, SUSAN ANNE · 2016 to 2020
$972k
NIAID NIH HHS K23 AI125715
6 · The paper itself

Abstract

A retrospective chart review characterized clinicians' use of maintenance intravaginal boric acid for women with recurrent vulvovaginal candidiasis or bacterial vaginosis. Average length of use was 13 months with high patient satisfaction and few adverse events. Prospective studies are needed to evaluate the efficacy of maintenance boric acid for these conditions.

Indexed as

Administration, IntravaginalAdultAnti-Infective Agents, LocalBoric AcidsCandidiasis, VulvovaginalDrug Administration ScheduleFemaleHumansMiddle AgedPatient SatisfactionRecurrenceRetrospective StudiesTreatment OutcomeVaginosis, BacterialAnti-Infective Agents, Localboric acidBoric Acids

Identifiers

PMID31663976
PMCPMC6878170
OpenAlexW2983033280

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.