ArticleeLife2019
Functional clustering of dendritic activity during decision-making.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
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Who cites it
91 citing papers in PubMed, 175 citations in OpenAlex.
- Tuft Dendrite Spikes Are Accompanied by Selective Input From Distinct Functional Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
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- Deep learning-assisted mapping of dendritic spines using sequential 2D two-photon calcium imaging.iScience · 2026Article
- Highly attenuated dendritic propagation of isolated synaptic potentials in vivo.Science advances · 2026Article
- Distinct types of dendritic CaScience advances · 2026Article
- Linking functional and structural dendritic spine remodeling during fear learning and extinction in vivo.Science advances · 2026Article
- Distinct sensorimotor encoding in tuft dendrites and somata associated with action, correction, and learning.bioRxiv : the preprint server for biology · 2026Article
- Functional organization of dendritic spines in mouse visual cortex layer 2/3 neurons.iScience · 2026Article
- Tuft dendrite spikes are accompanied by selective input from distinct functional networks.bioRxiv : the preprint server for biology · 2026Article
- Designer indicators for two-photon recording of subthreshold voltage dynamics.Nature methods · 2026Article
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- Chromatin remodelling subunit SMARCB1 is implicated in dendrite development and complex brain functions.Acta neuropathologica communications · 2026Article
- Spiking world model with multicompartment neurons for model-based reinforcement learning.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Autism-associatedProceedings of the National Academy of Sciences of the United States of America · 2025Article
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- Thalamocortical feedback selectively controls pyramidal neuron excitability.Nature communications · 2025Article
- DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning.Nature neuroscience · 2025Article
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- Sub-cellular population imaging tools reveal stable apical dendrites in hippocampal area CA3.Nature communications · 2025Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The active properties of dendrites can support local nonlinear operations, but previous imaging and electrophysiological measurements have produced conflicting views regarding the prevalence and selectivity of local nonlinearities in vivo. We imaged calcium signals in pyramidal cell dendrites in the motor cortex of mice performing a tactile decision task. A custom microscope allowed us to image the soma and up to 300 μm of contiguous dendrite at 15 Hz, while resolving individual spines. New analysis methods were used to estimate the frequency and spatial scales of activity in dendritic branches and spines. The majority of dendritic calcium transients were coincident with global events. However, task-associated calcium signals in dendrites and spines were compartmentalized by dendritic branching and clustered within branches over approximately 10 μm. Diverse behavior-related signals were intermingled and distributed throughout the dendritic arbor, potentially supporting a large learning capacity in individual neurons.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.