Evidence map›Paper›PMID 31663368›Full record

Trial reportAIDS research and human retroviruses2020

Short Communication: Early Antiretroviral Therapy Is Associated with Better Viral Suppression and Less HIV Drug Resistance After Implementation of Universal Treatment in South Africa.

Jienchi Dorward, Paul K Drain, Farzana Osman, Yukteshwar Sookrajh, Melendhran Pillay, Pravikrishnen Moodley, Nigel Garrett

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS research and human retroviruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. HIV Care Seeking Pathways and Barriers to the Continuum of Care Faced by Persons Living With HIV in Rural Nepal: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jienchi DorwardCentre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
Paul K DrainDepartment of Global Health, Schools of Medicine and Public Health, University of Washington, Seattle, Washington.
Farzana OsmanCentre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
Yukteshwar SookrajhPrince Cyril Zulu Communicable Disease Centre, eThekwini Municipality, Durban, South Africa.
Melendhran PillayDepartment of Virology, Inkosi Albert Luthuli Central Hospital, Cato Manor, Durban, South Africa.
Pravikrishnen MoodleyDepartment of Virology, Inkosi Albert Luthuli Central Hospital, Cato Manor, Durban, South Africa.
Nigel GarrettCentre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All people living with HIV should receive antiretroviral therapy (ART), but those with CD4 counts >500 cells/mm

Indexed as

AdultAnti-Retroviral AgentsCD4 Lymphocyte CountCross-Sectional StudiesDrug Resistance, ViralFemaleHIV InfectionsHumansMaleMedication AdherencePoint-of-Care SystemsRetrospective StudiesSecondary PreventionSouth AfricaTreatment OutcomeViral LoadAnti-Retroviral Agentsantiretroviral therapyHIV drug resistanceSouth Africauniversal treatmentviral load

Identifiers

PMID31663368
PMCPMC7185315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.