Evidence map›Paper›PMID 31663248›Full record

ArticleEMBO reports2019

In vivo optochemical control of cell contractility at single-cell resolution.

Deqing Kong, Zhiyi Lv, Matthias Häring, Benjamin Lin, Fred Wolf, Jörg Großhans

Open access · hybridAbstract read
In one paragraph

Article in EMBO reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Harnessing the Power ofCold Spring Harbor perspectives in biology · 2026
    Review
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  3. Article
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  8. Article
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  11. Optochemical Control of Cell Contractility in Drosophila Embryos.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  12. Review
  13. Article
  14. Review
  15. Planar Cell Polarity and E-Cadherin in Tissue-Scale Shape Changes inFrontiers in cell and developmental biology · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Deqing KongInstitute for Developmental Biochemistry, Georg-August-Universität Göttingen, Göttingen, Germany.ORCID 0000-0003-0672-4002
Zhiyi LvInstitute for Developmental Biochemistry, Georg-August-Universität Göttingen, Göttingen, Germany.
Matthias HäringBernstein Center for Computational Neuroscience, Göttingen, Germany.
Benjamin LinDepartment of Cell Biology, HHMI and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.
Fred WolfBernstein Center for Computational Neuroscience, Göttingen, Germany.
Jörg GroßhansInstitute for Developmental Biochemistry, Georg-August-Universität Göttingen, Göttingen, Germany.ORCID 0000-0003-1114-9233
Bernstein Center for Computational Neuroscience Göttingen · DEPhilipps University of Marburg · DENew York University · USUniversity of Göttingen · DE

Funding

Deutsche Forschungsgemeinschaft (DFG) FOR1756Deutsche Forschungsgemeinschaft (DFG) GR1945/6-1/2Deutsche Forschungsgemeinschaft (DFG) INST1525/16-1 FUGGDeutsche Forschungsgemeinschaft (DFG) SFB937/TP10Deutsche Forschungsgemeinschaft (DFG) WO1489/1
6 · The paper itself

Abstract

The spatial and temporal dynamics of cell contractility plays a key role in tissue morphogenesis, wound healing, and cancer invasion. Here, we report a simple optochemical method to induce cell contractions in vivo during Drosophila morphogenesis at single-cell resolution. We employed the photolabile Ca

Indexed as

AnimalsAnimals, Genetically ModifiedBiomechanical PhenomenaCalcium Chelating AgentsCalcium SignalingCell ShapeDrosophila melanogasterDrosophila ProteinsEgtazic AcidEpithelial CellsFemaleMyosin Type IIPhotochemical ProcessesSingle-Cell AnalysisSpatio-Temporal Analysis2-nitrophenyl-EGTACalcium Chelating AgentsDrosophila ProteinsEgtazic AcidMyosin Type IIactomyosinCa2+ uncagingcell contractilitymorphogenesisoptochemical

Identifiers

PMID31663248
PMCPMC6893293
OpenAlexW2982515077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.