Evidence map›Paper›PMID 31663157›Full record

ReviewBritish journal of clinical pharmacology2020

Heuristics for designing user-centric drug products: Lessons learned from Human Factors and Ergonomics.

Markus A Feufel, Gudrun Rauwolf, Felix C Meier, Fatma Karapinar-Çarkit, Maren Heibges

Abstract readReview
In one paragraph

Review in British journal of clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Markus A FeufelDepartment of Psychology and Ergonomics, Division of Ergonomics, Technische Universität Berlin, Berlin, Germany.ORCID 0000-0003-0563-8831
Gudrun RauwolfDepartment of Psychology and Ergonomics, Division of Ergonomics, Technische Universität Berlin, Berlin, Germany.
Felix C MeierDepartment of Psychology and Ergonomics, Division of Ergonomics, Technische Universität Berlin, Berlin, Germany.
Fatma Karapinar-ÇarkitDepartment of Clinical Pharmacy, OLVG, Amsterdam, The Netherlands.
Maren HeibgesDepartment of Psychology and Ergonomics, Division of Ergonomics, Technische Universität Berlin, Berlin, Germany.

Funding

Innovationsfonds beim gemeinsamen Bundesausschuss VSF1_2017-053
6 · The paper itself

Abstract

Even the most effective drug product may be used improperly and thus ultimately prove ineffective if it does not meet the perceptual, motor and cognitive capacities of its target users. Currently, no comprehensive guideline for systematically designing user-centric drug products that would help prevent such limitations exists. We have compiled a list of approximate but nonetheless useful strategies-heuristics-for implementing a user-centric design of drug products and drug product portfolios. First, we present a general heuristic for user-centric design based on the framework of Human Factors and Ergonomics (HF/E). Then we demonstrate how to implement this general heuristic for older drug users (i.e., patients and caregivers aged 65 years and older) and with respect to three specific challenges (use-cases) of medication management: (A) knowing what drug product to take/administer, (B) knowing how and when to take/administer it, and (C) actually taking/administering it. The presented heuristics can be applied prospectively to include existing knowledge about user-centric design at every step during drug discovery, pharmaceutical drug development, and pre-clinical and clinical trials. After a product has been released to the market, the heuristics may guide a retrospective analysis of medication errors and barriers to product usage as a basis for iteratively optimizing both the drug product and its portfolio over their life cycle.

Indexed as

HeuristicsPharmaceutical PreparationsDrug DevelopmentErgonomicsHumansRetrospective StudiesPharmaceutical Preparationsconsumer health informationdrug design and labellingergonomicshuman engineeringmedication errorspatient-centric designpatient safetyself-administrationuser-centric design

Identifiers

PMID31663157
PMCPMC7495287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.