Evidence map›Paper›PMID 31663156›Full record

Trial reportBritish journal of clinical pharmacology2020

Effectiveness of medication review on the number of drug-related problems in patients visiting the outpatient cardiology clinic: A randomized controlled trial.

Victor Johan Bernard Huiskes, Cornelia Helena Maria van den Ende, Martine Kruijtbosch, Hendrik Tinus Ensing, Marieke Meijs, Veronique Maria Mathea Meijs, David Marinus Burger, Bartholomeus Johannes Fredericus van den Bemt

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in British journal of clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Digital Health Interventions by Clinical Pharmacists: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Victor Johan Bernard HuiskesDepartment of Pharmacy, Sint Maartenskliniek, The Netherlands.ORCID 0000-0002-2120-354X
Cornelia Helena Maria van den EndeDepartment of Rheumatology, Sint Maartenskliniek, The Netherlands.
Martine KruijtboschSIR Institute for Pharmacy Practice and Policy, Leiden, The Netherlands.
Hendrik Tinus EnsingOutpatient Pharmacy, Flevoziekenhuis, Almere, The Netherlands.
Marieke MeijsOutpatient Pharmacy, St. Antonius ziekenhuis Nieuwegein, The Netherlands.
Veronique Maria Mathea MeijsOutpatient Pharmacy, LUMC, Leiden, The Netherlands.
David Marinus BurgerDepartment of pharmacy, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-7279-2818
Bartholomeus Johannes Fredericus van den BemtDepartment of Pharmacy, Sint Maartenskliniek, The Netherlands.
Radboud University Nijmegen · NLSint Maartenskliniek · NLFlevoziekenhuis · NLLeiden University Medical Center · NLSIR Institute for Pharmacy Practice and Policy · NLSt. Antonius Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo assess the effectiveness of medication review on the number of drug-related problems (DRPs) in outpatient cardiology patients.

methodsIn this randomized controlled trial, a computer-assisted and pharmacist-led medication review with patient involvement (questionnaire and telephone call with pharmacist) was conducted in intervention patients prior to their visit to the cardiologist. The control group received usual care. Adult outpatient cardiology patients without support concerning the administration of medication, without a medication review in the past 6 months and who gave permission to access their electronic medication record were included. The primary outcome measure was the number of DRPs 1 month after the visit. Secondary outcome measures concerned the type of DRP and the type of medication involved in the DRPs.

resultsIn total, 75 patients (mean [standard deviation, SD] age 66.0 [12.5] years, 41% female) were included. Intervention (n = 90) and control group (n = 85) were comparable at baseline. The mean (SD) number of drugs used per patient was 7.9 (3.9). After 1 month, the mean (SD) number of DRPs was 0.3 (0.7) and 0.8 (1.0) and the median (range) number of DRPs was 0 (0-4) and 0 (0-4) in the intervention group and control group, respectively (P < .001). In the intervention group, 74% of the DRPs identified at T0 were solved at T1 vs 14% in the control group.

conclusionThis randomized controlled trial suggests that a pharmacist-led medication review in patients with a scheduled visit to the outpatient cardiology clinic decreases the number of DRPs.

Indexed as

CardiologyDrug-Related Side Effects and Adverse ReactionsPharmaceutical PreparationsAdultAgedFemaleHumansMaleOutpatientsPharmacistsPharmaceutical Preparationsclinical pharmacologydrug developmentdrug safetydrug utilizationprescribingquality use of medicinesrandomised controlled trial

Identifiers

PMID31663156
PMCPMC6983519
OpenAlexW2982509731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.