Evidence map›Paper›PMID 31663029›Full record

ReviewScience advances2019

Current advances in research in treatment and recovery: Nicotine addiction.

Judith J Prochaska, Neal L Benowitz

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06765824 (Transcranial Magnetic Stimulation in the Treatment of Dual Disorders), which is not on this map. Cited by 100 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 3 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06765824 phase3not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Transcranial Magnetic Stimulation in the Treatment of Dual Disorders: Study in Patients with Depression and Tobacco Addiction

TypeinterventionalSponsorCardenal Herrera UniversityRan2025 to 2026Enrolled36ConditionsMajor Depression, Tobacco AddictionArmsRepetitive Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham
3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 3 syntheses or guidelines pooled it, 210 citations in OpenAlex.

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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Judith J ProchaskaStanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0001-7925-326X
Neal L BenowitzProgram in Clinical Pharmacology, Division of Cardiology, and the Center for Tobacco Control Research and Education, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2041-8124
Stanford University · USUniversity of California, San Francisco · US

Funding

PROJECT 5: IMPACT OF CHANGING TOBACCO PRODUCT USE ON HEALTHCARE COSTS FOR GENERAL AND VULNERABLE POPULATIONSU54HL147127 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CALFEE, CAROLYN · 2018 to 2022
$20.4M
Project 3: Tobacco Town Policy ModelingP01CA225597 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HENRIKSEN, LISA ANNE, LUKE, DOUGLAS A · 2018 to 2023
$11.5M
Technology Innovations for Supporting Health in Alaska Native PeopleR01HL117736 · NHLBI · STANFORD UNIVERSITY · PI BENOWITZ, NEAL L, PROCHASKA, JUDITH J. · 2014 to 2018
$3.8M
NCI NIH HHS P01 CA225597NHLBI NIH HHS R01 HL117736NHLBI NIH HHS U54 HL147127
6 · The paper itself

Abstract

The health harms of combusted tobacco use are undeniable. With market and regulatory pressures to reduce the harms of nicotine delivery by combustion, the tobacco product landscape has diversified to include smokeless, heated, and electronic nicotine vaping products. Products of tobacco combustion are the main cause of smoking-induced disease, and nicotine addiction sustains tobacco use. An understanding of the biology and clinical features of nicotine addiction and the conditioning of behavior that occurs via stimuli paired with frequent nicotine dosing, as with a smoked cigarette, is important for informing pharmacologic and behavioral treatment targets. We review current advances in research on nicotine addiction treatment and recovery, with a focus on conventional combustible cigarette use. Our review covers evidence-based methods to treat smoking in adults and policy approaches to prevent nicotine product initiation in youth. In closing, we discuss emerging areas of evidence and consider new directions for advancing the field.

Indexed as

AnimalsHumansNicotineSmokingTobacco ProductsTobacco Use DisorderNicotine

Identifiers

PMID31663029
PMCPMC6795520
OpenAlexW2981148845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.