Evidence map›Paper›PMID 31662952›Full record

ArticleExpert opinion on orphan drugs2018

Is there potential for the approval of monoclonal antibodies to treat thyroid-associated ophthalmopathy?

Terry J Smith

Abstract read
In one paragraph

Article in Expert opinion on orphan drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Cytokines in Thyroid-Associated Ophthalmopathy.Journal of immunology research · 2022
    Review
  3. Thyroid Eye Disease: Navigating the New Treatment Landscape.Journal of the Endocrine Society · 2021
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Terry J SmithUniversity of Michigan Ringgold standard institution - Ophthalmology and Visual Sciences, Ann Arbor, Michigan, USA.

Funding

REGULATION OF RETROOCULAR CONNECTIVE TISSUER01EY008976 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SMITH, TERRY J · 1993 to 2020
$6.4M
NEI NIH HHS R01 EY008976
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AutoimmuneGraves’ diseaseInsulin-like growth factor-I receptorMonoclonal antibody

Identifiers

PMID31662952
PMCPMC6818270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.