ReviewTherapeutic advances in chronic disease2019
Common risk factors for major noncommunicable disease, a systematic overview of reviews and commentary: the implied potential for targeted risk reduction.
Review in Therapeutic advances in chronic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 6 syntheses or guidelines pooled it, 225 citations in OpenAlex.
- Multimorbidity and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies.The journal of prevention of Alzheimer's disease · 2025Pooled it
- Burden of metabolic syndrome in the global adult HIV-infected population: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Epidemiology of non-communicable diseases among professional drivers in LMICs: a systematic review and meta-analysis.Health promotion international · 2024Pooled it
- Pooled it
- Barriers and facilitators to dissemination of non-communicable diseases research: a mixed studies systematic review.Frontiers in public health · 2024Pooled it
- Effectiveness of eHealth Interventions Targeting Employee Health Behaviors: Systematic Review.Journal of medical Internet research · 2023Pooled it
- An Internet-Based Intervention Augmented With a Diet and Physical Activity Consultation to Decrease the Risk of Dementia in At-Risk Adults in a Primary Care Setting: Pragmatic Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Biopsychosocial frailty and the incident risk of cardio- and cerebrovascular diseases: an 8-year follow-up of the italian longitudinal study on aging.GeroScience · 2026Article
- Remote coaching with blood flow restriction training: impact on strength, body composition, metabolism, and walking energetics in overweight adults.European journal of applied physiology · 2026Article
- Obesogenic Diets Composition Differentially Alters theNutrients · 2026Article
- Potential impact of increasing physical activity on NCD mortality in the EU: pathways to SDG 3.4.1 by 2030.BMJ global health · 2026Article
- First population-based study on non-communicable diseases and risk factors in northeastern Iran: Sabzevar cohort profile.BMJ open · 2026Article
- Feasibility of identifying factors related to Alzheimer's disease and related dementia in real-world data.JAMIA open · 2026Review
- Placement-Dependent Accuracy of a Smartphone-Based Sensor Application Compared to an Accelerometer-Based System for Measuring Physical Activity in Healthy Adults: A Validation Study.Sensors (Basel, Switzerland) · 2026Article
- Nutrition knowledge and healthy-eating attitudes: the role of physical activity and lifestyle factors in adults.Frontiers in nutrition · 2026Article
- Article
- The Interaction of Health Behaviors and Cardiovascular Diseases: Investigating Morbidity Risks of Disparities in U.S. Adults.Healthcare (Basel, Switzerland) · 2025Article
- Trends in smoking tobacco in Africa, 1990-2019: analysis from the global burden of disease study 2019.BMC public health · 2025Article
- PACAP Signalling Network in the Nucleus Accumbens Core Regulates Reinstatement Behaviour in Rat.Addiction biology · 2025Article
- The Effects of Alpha Linolenic Acid (Omega-3 Fatty Acid) on Tobacco Craving Intensity, Withdrawal Symptoms and Biochemical Markers in Tobacco Users.Indian journal of clinical biochemistry : IJCB · 2025Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Noncommunicable disease now contributes to the World Health Organization top 10 causes of death in low-, middle- and high-income countries. Particular examples include stroke, coronary heart disease, dementia and certain cancers. Research linking clinical and lifestyle risk factors to increased risk of noncommunicable disease is now well established with examples of confirmed risk factors, including smoking, physical inactivity, obesity and hypertension. However, despite a need to target our resources to achieve risk reduction, relatively little work has examined the overlap between the risk factors for these main noncommunicable diseases. Our high-level review draws together the evidence in this area. Using a systematic overview of reviews, we demonstrate the likely commonality of established risk factors having an impact on multiple noncommunicable disease outcomes. For example, systematic reviews of the evidence on physical inactivity and poor diet found each to be associated with increased risk of cancers, coronary heart disease, stroke, diabetes mellitus and dementia. We highlight the potential for targeted risk reduction to simultaneously impact multiple noncommunicable disease areas. These relationships now need to be further quantified to allow the most effective development of public health interventions in this area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.