Evidence map›Paper›PMID 31662770›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2019

Therapeutic Efficacy of Kangfuxin Liquid Combined with PPIs in Gastric Ulcer.

Jun-Bo Zou, Xiao-Fei Zhang, Ya-Jun Shi, Jia Tai, Yu Wang, Yu-Lin Liang, Fang Wang, Jiang-Xue Cheng, Jing Wang, Dong-Yan Guo

Open access · hybridAbstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Link between mutations inWorld journal of gastrointestinal surgery · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Gastroprotective Effects ofFrontiers in pharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jun-Bo ZouShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.ORCID https://orcid.org/0000-0002-1651-4722
Xiao-Fei ZhangShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.
Ya-Jun ShiShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.ORCID https://orcid.org/0000-0003-1178-5504
Jia TaiShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.
Yu WangShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.
Yu-Lin LiangShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.
Fang WangKey Laboratory of Modern Prepararation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Jiang-Xue ChengShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.
Jing WangShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.
Dong-Yan GuoShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research; Pharmacy College, Shaanxi University of Chinese Medicine, Xianyang, China.
Shaanxi University of Chinese Medicine · CNJiangxi University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical efficacy and safety of Kangfuxin liquid (KFX) combined with proton pump inhibitors (PPIs) in the treatment of gastric ulcer (GU). MATERIALS AND

methodsElectronic databases including PubMed, Wanfang, CNKI, VIP, Embase, Cochrane Library, and CBM were examined for appropriate articles without language limitations on key words before March 10, 2019. RevMan 5.3 software was applied to execute outcome assessment and finish the meta-analysis.

results22 articles involving 2,024 patients with a gastric ulcer were selected. Total efficacy rate and efficacy rate of gastroscopy were significantly enhanced for the combination of KFX with PPIs compared to those of PPI treatment alone (OR = 6.95, 95% CI: 4.87, 9.91,

conclusionKFX combined with PPIs in treatment of patients with GU could improve the total efficacy rate and efficacy rate of gastroscopy and reduce adverse events and the recurrence rate. However, the results of this study should be handled with care due to the limitations. Several rigorous RCTs are in need to confirm these findings.

Identifiers

PMID31662770
PMCPMC6791226
OpenAlexW2977556508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.