Evidence map›Paper›PMID 31662757›Full record

ArticleJournal of oncology2019

MicroRNA-181a Inhibits Activated B-Cell-Like Diffuse Large B-Cell Lymphoma Progression by Repressing

Danxia Zhu, Cheng Fang, Wenting He, Chen Wu, Xiaodong Li, Jun Wu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Regulation of Metastasis and Growth of Colorectal CancerRecent patents on anti-cancer drug discovery · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Danxia ZhuDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Cheng FangDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Wenting HeDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Chen WuDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Xiaodong LiDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.ORCID https://orcid.org/0000-0001-8676-0489
Jun WuDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou, China.ORCID https://orcid.org/0000-0002-6706-1735
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the role of miR-181a in diffuse large B-cell lymphoma (DLBCL) and its potential target genes. miR-181a levels were lower in activated B-cell- (ABC-) like DLBCL cells than that in germinal center B-cell- (GCB-) like DLBCL cells. Overexpression of miR-181a in ABC-like DLBCL cell lines (OCI-LY10 and U2932) resulted in G0/G1 cell cycle arrest, increased apoptosis, and decreased invasiveness. miRNA target prediction programs (miRanda, TargetScan, and miRDB) identified caspase recruitment domain-containing protein 11 (

Identifiers

PMID31662757
PMCPMC6778910
OpenAlexW2977054928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.