Evidence map›Paper›PMID 31662587›Full record

ArticleThe Review of economic studies2019

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules.

Pierre Azoulay, Danielle Li, Joshua S Graff Zivin, Bhaven N Sampat

Abstract read
In one paragraph

Article in The Review of economic studies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. The rise of large language models and the direction and impact of US federal research funding.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Recognizing NIH's Role in Turning Discoveries into Cancer Treatments.LES nouvelles. Licensing Executives Society (U.S.A.) · 2026
    Article
  5. Article
  6. Video game engines as the new "virtual" Skinner box.Journal of the experimental analysis of behavior · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Strategic policy options to improve quality and productivity of biomedical research.Politics and the life sciences : the journal of the Association for Politics and the Life Sciences · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. What Can Economics Say about Alzheimer's Disease?Journal of economic literature · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Pierre AzoulayMIT & NBER.
Danielle LiHarvard University.
Joshua S Graff ZivinUCSD & NBER.
Bhaven N SampatColumbia University & NBER.

Funding

LIFE CYCLE EVENTS, PRODUCTIVITY, AND SCIENTIFIC IMPACTP01AG039347 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI WEINBERG, BRUCE A · 2013 to 2018
$5.4M
NIA NIH HHS P01 AG039347
6 · The paper itself

Abstract

We quantify the impact of scientific grant funding at the National Institutes of Health (NIH) on patenting by pharmaceutical and biotechnology firms. Our paper makes two contributions. First, we use newly constructed bibliometric data to develop a method for flexibly linking specific grant expenditures to private-sector innovations. Second, we take advantage of idiosyncratic rigidities in the rules governing NIH peer review to generate exogenous variation in funding across research areas. Our results show that NIH funding spurs the development of private-sector patents: a $10 million boost in NIH funding leads to a net increase of 2.3 patents. Though valuing patents is difficult, we report a range of estimates for the private value of these patents using different approaches.

Indexed as

academic researcheconomics of scienceknowledge spilloversNIHpatenting

Identifiers

PMID31662587
PMCPMC6818650

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.