Evidence map›Paper›PMID 31662557›Full record

SynthesisIn vivo (Athens, Greece)

Pelvic Exenteration for Locally Advanced and Relapsed Pelvic Malignancies - An Analysis of 100 Cases.

Nicolae Bacalbasa, Irina Balescu, Mihaela Vilcu, Adrian Neacsu, Simona Dima, Adina Croitoru, Iulian Brezean

Open access · diamondAbstract readMeta-Analysis
In one paragraph

Synthesis in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Nicolae Bacalbasa *"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Irina Balescu"Ponderas" Academic Hospital, Bucharest, Romania irina.balescu@ponderas-ah.ro.
Mihaela Vilcu"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Adrian Neacsu"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Simona Dima"Fundeni" Clinical Institute - Center of Excellence in Translational Medicine, Bucharest, Romania.
Adina Croitoru *"Fundeni" Clinical Institute - Center of Excellence in Translational Medicine, Bucharest, Romania.
Iulian Brezean"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROInstitutul Cantacuzino · ROClinical Emergency Hospital Bucharest · ROInstitutul Clinic Fundeni · ROTitu Maiorescu University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAlthough pelvic exenteration is an aggressive surgical procedure, it remains almost the only curative solution for patients diagnosed with large pelvic malignancies. PATIENTS AND

methodsWe present a series of 100 patients submitted to pelvic exenteration with curative intent.

resultsThe origin of the primary tumor was most commonly represented by cervical cancer, followed by, endometrial cancer, rectal cancer, ovarian cancer and vulvo-vaginal cancer. An R0 resection was confirmed in 68 cases, while the remaining 32 cases presented lateral positive resection margins or perineal positive margins. The postoperative morbidity rate was 37% while the mortality rate was 3%. As for the-long term outcomes, the median overall survival time was 38.7 months, being most significantly influenced by the origin of the primary tumor.

conclusionAlthough pelvic exenteration is still associated with an increased morbidity, an important improvement in the long-term survival can be achieved, especially if radical resection is feasible.

Indexed as

Pelvic ExenterationAdultAgedDisease ManagementFemaleHumansMaleMiddle AgedNeoplasm GradingNeoplasm Recurrence, LocalNeoplasm StagingPelvic NeoplasmsPrognosisTreatment OutcomeTumor BurdencurativePelvic exenterationsurvival

Identifiers

PMID31662557
PMCPMC6899142
OpenAlexW2984417705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.